LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 929 1593 3216 0.4953 0.3511
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 929 1246 3216 0.3875 0.1781
Hs 578T PHA-793887
3.33
uM
LJP6
 72
hr
 929 1057 3216 0.3288 0.0749
Hs 578T PHA-793887
10
uM
LJP6
 72
hr
 929 836 3216 0.2598 -0.0582
Hs 578T QL-X-138
0.04
uM
LJP6
 72
hr
 929 2741 3216 0.8521 0.8288
Hs 578T QL-X-138
0.12
uM
LJP6
 72
hr
 929 2453 3216 0.7627 0.7192
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 929 2212 3216 0.6878 0.6226
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 929 1970 3216 0.6124 0.5209
Hs 578T QL-X-138
3.33
uM
LJP6
 72
hr
 929 1786 3216 0.5555 0.4402
Hs 578T QL-X-138
10
uM
LJP6
 72
hr
 929 980 3216 0.3047 0.0301
Hs 578T QL-XII-47
0.04
uM
LJP6
 72
hr
 929 3047 3216 0.9476 0.9408
Hs 578T QL-XII-47
0.12
uM
LJP6
 72
hr
 929 3032 3216 0.9426 0.9351
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 929 2623 3216 0.8157 0.7850
Hs 578T QL-XII-47
1.11
uM
LJP6
 72
hr
 929 1965 3216 0.6110 0.5187
Hs 578T QL-XII-47
3.33
uM
LJP6
 72
hr
 929 1321 3216 0.4109 0.2173
Hs 578T QL-XII-47
10
uM
LJP6
 72
hr
 929 822 3216 0.2554 -0.0675
Hs 578T Torin1
0.04
uM
LJP6
 72
hr
 929 1429 3216 0.4445 0.2719
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 868 914 3556 0.2569 0.0248
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 929 1391 3216 0.4325 0.2522
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 72
hr
 868 882 3556 0.2483 0.0079
Hs 578T Torin1
0.37
uM
LJP6
 72
hr
 929 1314 3216 0.4087 0.2136
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 868 827 3556 0.2332 -0.0231
Hs 578T Torin1
1.11
uM
LJP6
 72
hr
 929 1237 3216 0.3848 0.1728
MDA-MB-231 Mitoxantrone
1.11
uM
LJP6
 72
hr
 868 718 3556 0.2023 -0.0887
Hs 578T Torin1
3.33
uM
LJP6
 72
hr
 929 1146 3216 0.3564 0.1238