LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1343 | 3772 | 0.3560 | -0.0680 |
| SK-BR-3 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1476 | 1410 | 3772 | 0.3736 | -0.0347 |
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3944 | 3772 | 1.0455 | 1.0661 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4191 | 3772 | 1.1110 | 1.1614 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4182 | 3772 | 1.1088 | 1.1588 |
| SK-BR-3 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3658 | 3772 | 0.9697 | 0.9537 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1055 | 3772 | 0.2796 | -0.2214 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 1476 | 662 | 3772 | 0.1758 | -0.4476 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 3883 | 3772 | 1.0294 | 1.0433 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2696 | 3772 | 0.7149 | 0.5605 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 2147 | 3772 | 0.5694 | 0.3186 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1485 | 3772 | 0.3938 | 0.0042 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1433 | 3772 | 0.3800 | -0.0219 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 72 | hr | 1476 | 1383 | 3772 | 0.3668 | -0.0479 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3474 | 3643 | 0.9536 | 0.9279 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2882 | 3643 | 0.7908 | 0.6683 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1424 | 3643 | 0.3896 | -0.0329 |
| SK-BR-3 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1243 | 3643 | 0.3401 | -0.1289 |
| SK-BR-3 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1476 | 963 | 3643 | 0.2636 | -0.2843 |
| SK-BR-3 | Celastrol | 10 | uM | LJP6 | 72 | hr | 1476 | 1002 | 3643 | 0.2760 | -0.2574 |
| SK-BR-3 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4337 | 3772 | 1.1497 | 1.2170 |
| SK-BR-3 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4204 | 3772 | 1.1147 | 1.1673 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4224 | 3772 | 1.1201 | 1.1751 |
| SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3901 | 3772 | 1.0341 | 1.0498 |
| SK-BR-3 | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 3556 | 3772 | 0.9427 | 0.9143 |