LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 CP724714
1.11
uM
LJP5
 72
hr
 1657 4568 5588 0.8175 0.7827
BT-20 CP724714
10
uM
LJP5
 72
hr
 1657 3680 5588 0.6587 0.5760
BT-20 Alvocidib
0.04
uM
LJP6
 72
hr
 1657 2798 5383 0.5198 0.3606
BT-20 Alvocidib
3.33
uM
LJP6
 72
hr
 1657 1188 5383 0.2204 -0.1805
BT-20 Alvocidib
10
uM
LJP6
 72
hr
 1657 1169 5383 0.2165 -0.1898
BT-20 GW843682X
0.12
uM
LJP6
 72
hr
 1657 3476 5383 0.6456 0.5456
BT-20 GW843682X
0.37
uM
LJP6
 72
hr
 1657 2170 5383 0.4027 0.1696
BT-20 GW843682X
10
uM
LJP6
 72
hr
 1657 1730 5383 0.3210 0.0238
BT-20 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1657 5252 5588 0.9399 0.9300
BT-20 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1657 4390 5588 0.7861 0.7411
BT-20 HG-5-113-01
1.11
uM
LJP5
 72
hr
 1657 3826 5588 0.6848 0.6114
BT-20 HG-5-88-01
1.11
uM
LJP6
 72
hr
 1657 4985 5383 0.9258 0.9107
BT-20 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1657 4472 5383 0.8310 0.7936
BT-20 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1657 5824 5383 1.0838 1.0974
BT-20 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1657 5436 5383 1.0111 1.0135
BT-20 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1657 2994 5383 0.5567 0.4163
BT-20 HG-6-64-01
10
uM
LJP6
 72
hr
 1657 904 5383 0.1679 -0.3007
BT-20 Neratinib
0.12
uM
LJP5
 72
hr
 1657 4407 5588 0.7888 0.7469
BT-20 Neratinib
0.37
uM
LJP5
 72
hr
 1657 4244 5588 0.7597 0.7095
BT-20 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1657 4770 5383 0.8867 0.8631
BT-20 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1657 5194 5383 0.9643 0.9570
BT-20 JW-7-24-1
1.11
uM
LJP6
 72
hr
 1657 4510 5383 0.8379 0.8023
BT-20 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1657 4050 5383 0.7525 0.6918
BT-20 PF562271
10
uM
LJP6
 72
hr
 1657 1301 5383 0.2415 -0.1346
BT-20 PF562271
3.33
uM
LJP6
 72
hr
 1657 1962 5383 0.3646 0.1040