LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 ZSTK474
0.12
uM
LJP6
 72
hr
 1657 4895 5383 0.9102 0.8926
SK-BR-3 ZSTK474
0.37
uM
LJP6
 72
hr
 1476 1877 3643 0.5154 0.2001
SK-BR-3 ZSTK474
3.33
uM
LJP6
 72
hr
 1476 1478 3643 0.4072 0.0017
SK-BR-3 ZSTK474
1.11
uM
LJP6
 72
hr
 1476 1575 3643 0.4319 0.0475
SK-BR-3 ZSTK474
0.04
uM
LJP6
 72
hr
 1476 3090 3643 0.8474 0.7592
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1235 3330 4056 0.8218 0.7833
SK-BR-3 ZSTK474
0.12
uM
LJP6
 72
hr
 1476 2435 3643 0.6680 0.4654
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 929 2659 3216 0.8269 0.7986
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 929 2261 3216 0.7031 0.6429
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 72
hr
 868 2729 3556 0.7678 0.7564
MCF7 ZSTK474
10
uM
LJP6
 72
hr
 1235 1338 4056 0.3303 0.0476
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 868 3142 3410 0.9205 0.9165
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 868 2841 3410 0.8328 0.8224
MCF7 YM 201636
10
uM
LJP5
 72
hr
 1235 1809 4267 0.4241 0.2376
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 868 2657 3410 0.7798 0.7633
MDA-MB-231 YM 201636
10
uM
LJP5
 72
hr
 868 1597 3410 0.4688 0.3619
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1657 4646 5588 0.8315 0.7992
BT-20 YM 201636
0.12
uM
LJP5
 72
hr
 1657 5446 5588 0.9746 0.9707
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1657 5135 5588 0.9188 0.9047
BT-20 YM 201636
3.33
uM
LJP5
 72
hr
 1657 3958 5588 0.7082 0.6424
BT-20 YM 201636
10
uM
LJP5
 72
hr
 1657 2142 5588 0.3833 0.1571
SK-BR-3 YM 201636
10
uM
LJP5
 72
hr
 1476 1748 3772 0.4634 0.1327
SK-BR-3 YM 201636
3.33
uM
LJP5
 72
hr
 1476 3060 3772 0.8113 0.7132
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 868 3322 3410 0.9724 0.9688
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1235 4588 4267 1.0741 1.0800