LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 513 11110 10473 1.0608 1.0273
MCF 10A Alvocidib
0.04
uM
LJP6
 72
hr
 513 1211 10473 0.1157 0.2180
MCF 10A Alvocidib
3.33
uM
LJP6
 72
hr
 513 505 10473 0.0482 -0.0038
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 513 486 10473 0.0464 -0.0146
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 513 452 10473 0.0432 -0.0298
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 513 9912 10473 0.9465 0.9748
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 513 3341 10473 0.3189 0.5362
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 513 6501 10473 0.6206 0.7920
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 513 2003 10473 0.1913 0.3672
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 513 7852 10473 0.7495 0.8710
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 513 995 10473 0.0950 0.1636
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 513 665 10473 0.0636 0.0613
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 513 482 10473 0.0461 -0.0150
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 513 1722 10473 0.1645 0.3189
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 513 936 10473 0.0894 0.1480
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 513 2503 10473 0.2388 0.4339
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 513 1215 10473 0.1160 0.2178
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 513 927 10473 0.0885 0.1425
MCF 10A AZD8055
10
uM
LJP6
 72
hr
 513 840 10473 0.0802 0.1194
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 513 10401 10473 0.9931 0.9965
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 513 10330 10473 0.9863 0.9936
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 513 467 10473 0.0447 -0.0214
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 513 6249 10473 0.5967 0.7760
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 513 9173 10473 0.8762 0.9394
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 513 9324 10473 0.8905 0.9473