LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GDC-0980
0.37
uM
LJP5
 72
hr
 513 967 10362 0.0933 0.1567
MCF 10A GDC-0980
1.11
uM
LJP5
 72
hr
 513 641 10362 0.0619 0.0506
MCF 10A GDC-0980
3.33
uM
LJP5
 72
hr
 513 603 10362 0.0583 0.0380
MCF 10A GDC-0980
10
uM
LJP5
 72
hr
 513 572 10362 0.0552 0.0241
MCF 10A Mitoxantrone
0.04
uM
LJP5
 72
hr
 513 1036 10362 0.1000 0.1759
MCF 10A Mitoxantrone
0.04
uM
LJP6
 72
hr
 513 907 10473 0.0867 0.1399
MCF 10A Mitoxantrone
0.12
uM
LJP5
 72
hr
 513 662 10362 0.0639 0.0533
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 513 690 10473 0.0659 0.0694
MCF 10A Mitoxantrone
0.37
uM
LJP5
 72
hr
 513 555 10362 0.0536 0.0166
MCF 10A Mitoxantrone
0.37
uM
LJP6
 72
hr
 513 552 10473 0.0527 0.0165
MCF 10A Mitoxantrone
1.11
uM
LJP5
 72
hr
 513 387 10362 0.0373 -0.0633
MCF 10A Mitoxantrone
1.11
uM
LJP6
 72
hr
 513 458 10473 0.0438 -0.0267
MCF 10A Mitoxantrone
3.33
uM
LJP5
 72
hr
 513 371 10362 0.0358 -0.0722
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 513 407 10473 0.0389 -0.0529
MCF 10A Mitoxantrone
10
uM
LJP5
 72
hr
 513 403 10362 0.0389 -0.0545
MCF 10A Mitoxantrone
10
uM
LJP6
 72
hr
 513 464 10473 0.0443 -0.0231
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 513 6621 10362 0.6390 0.8035
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 513 6388 10473 0.6099 0.7849
MCF 10A Radicicol
0.12
uM
LJP5
 72
hr
 513 1750 10362 0.1692 0.3232
MCF 10A Radicicol
0.12
uM
LJP6
 72
hr
 513 1851 10473 0.1768 0.3407
MCF 10A Radicicol
0.37
uM
LJP5
 72
hr
 513 794 10362 0.0767 0.1045
MCF 10A Radicicol
0.37
uM
LJP6
 72
hr
 513 841 10473 0.0803 0.1191
MCF 10A Radicicol
1.11
uM
LJP5
 72
hr
 513 720 10362 0.0696 0.0794
MCF 10A Radicicol
1.11
uM
LJP6
 72
hr
 513 742 10473 0.0709 0.0843
MCF 10A Radicicol
3.33
uM
LJP5
 72
hr
 513 638 10362 0.0617 0.0493