LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 513 | 539 | 10362 | 0.0521 | 0.0113 |
| MCF 10A | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 513 | 507 | 10473 | 0.0485 | -0.0032 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 513 | 494 | 10362 | 0.0477 | -0.0105 |
| MCF 10A | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 513 | 473 | 10473 | 0.0452 | -0.0187 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP5 | 72 | hr | 513 | 389 | 10362 | 0.0376 | -0.0630 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP6 | 72 | hr | 513 | 393 | 10473 | 0.0375 | -0.0601 |
| MCF 10A | Geldanamycin | 10 | uM | LJP5 | 72 | hr | 513 | 307 | 10362 | 0.0297 | -0.1119 |
| MCF 10A | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 513 | 262 | 10473 | 0.0250 | -0.1442 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10774 | 10362 | 1.0399 | 1.0179 |
| MCF 10A | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 513 | 9871 | 10362 | 0.9529 | 0.9771 |
| MCF 10A | YM 201636 | 0.37 | uM | LJP5 | 72 | hr | 513 | 8987 | 10362 | 0.8675 | 0.9352 |
| MCF 10A | YM 201636 | 1.11 | uM | LJP5 | 72 | hr | 513 | 6499 | 10362 | 0.6271 | 0.7952 |
| MCF 10A | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 513 | 5196 | 10362 | 0.5015 | 0.7044 |
| MCF 10A | YM 201636 | 10 | uM | LJP5 | 72 | hr | 513 | 1389 | 10362 | 0.1341 | 0.2576 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 513 | 10892 | 10362 | 1.0515 | 1.0230 |
| MCF 10A | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 513 | 10711 | 10362 | 1.0337 | 1.0153 |
| MCF 10A | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 513 | 10898 | 10362 | 1.0517 | 1.0233 |
| MCF 10A | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 513 | 10220 | 10362 | 0.9862 | 0.9936 |
| MCF 10A | TWS119 | 3.33 | uM | LJP5 | 72 | hr | 513 | 6437 | 10362 | 0.6214 | 0.7920 |
| MCF 10A | TWS119 | 10 | uM | LJP5 | 72 | hr | 513 | 385 | 10362 | 0.0372 | -0.0639 |
| MCF 10A | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 513 | 9417 | 10362 | 0.9089 | 0.9563 |
| MCF 10A | PF477736 | 0.12 | uM | LJP5 | 72 | hr | 513 | 8819 | 10362 | 0.8513 | 0.9269 |
| MCF 10A | PF477736 | 0.37 | uM | LJP5 | 72 | hr | 513 | 7576 | 10362 | 0.7311 | 0.8605 |
| MCF 10A | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 513 | 3600 | 10362 | 0.3471 | 0.5645 |
| MCF 10A | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 513 | 931 | 10362 | 0.0899 | 0.1469 |