LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 1209 3993 4376 0.9125 0.9036
MCF7 Brivanib
10
uM
LJP5
 1
P13
 72
hr
 1209 3573 3980 0.8977 0.8783
MCF7 Brivanib
10
uM
LJP5
 2
P13
 72
hr
 1209 4001 4252 0.9408 0.9338
MCF7 Brivanib
10
uM
LJP5
 3
P13
 72
hr
 1209 3889 4376 0.8887 0.8767
MCF7 CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 1209 3634 3823 0.9506 0.9399
MCF7 CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 1209 3807 4093 0.9299 0.9191
MCF7 CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 1209 3767 4121 0.9141 0.9009
MCF7 CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 1209 3612 3823 0.9448 0.9328
MCF7 CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 1209 3695 4093 0.9026 0.8868
MCF7 CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 1209 3516 4121 0.8532 0.8282
MCF7 CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 1209 3438 3823 0.8993 0.8761
MCF7 CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 1209 3692 4093 0.9018 0.8859
MCF7 CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 1209 3690 4121 0.8954 0.8788
MCF7 CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 1209 3124 3823 0.8172 0.7710
MCF7 CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 1209 3252 4093 0.7944 0.7546
MCF7 CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 1209 3351 4121 0.8131 0.7792
MCF7 CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 1209 2734 3823 0.7152 0.6343
MCF7 CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 1209 3156 4093 0.7709 0.7250
MCF7 CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 1209 3213 4121 0.7796 0.7374
MCF7 CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 1209 1845 3823 0.4826 0.2896
MCF7 CHIR-99021
10
uM
LJP6
 2
P13
 72
hr
 1209 2025 4093 0.4946 0.3404
MCF7 CHIR-99021
10
uM
LJP6
 3
P13
 72
hr
 1209 1770 4121 0.4295 0.2402
MCF7 Linifanib
0.04
uM
LJP6
 1
J12
 72
hr
 1209 3748 3823 0.9804 0.9763
MCF7 Linifanib
0.04
uM
LJP6
 2
J12
 72
hr
 1209 4159 4093 1.0159 1.0180
MCF7 Linifanib
0.04
uM
LJP6
 3
J12
 72
hr
 1209 4107 4121 0.9966 0.9961