LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Linsitinib
0.37
uM
LJP5
 3
O22
 72
hr
 962 9878 10315 0.9576 0.9749
MCF 10A Linsitinib
1.11
uM
LJP5
 1
O21
 72
hr
 962 9335 10714 0.8713 0.9223
MCF 10A Linsitinib
1.11
uM
LJP5
 2
O21
 72
hr
 962 9708 10507 0.9239 0.9546
MCF 10A Linsitinib
1.11
uM
LJP5
 3
O21
 72
hr
 962 9435 10315 0.9147 0.9486
MCF 10A Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 962 8837 10714 0.8248 0.8922
MCF 10A Linsitinib
3.33
uM
LJP5
 2
O20
 72
hr
 962 9357 10507 0.8905 0.9339
MCF 10A Linsitinib
3.33
uM
LJP5
 3
O20
 72
hr
 962 8998 10315 0.8723 0.9217
MCF 10A Linsitinib
10
uM
LJP5
 1
O19
 72
hr
 962 8420 10714 0.7859 0.8661
MCF 10A Linsitinib
10
uM
LJP5
 2
O19
 72
hr
 962 8730 10507 0.8308 0.8954
MCF 10A Linsitinib
10
uM
LJP5
 3
O19
 72
hr
 962 8689 10315 0.8424 0.9022
MCF 10A Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 962 10454 10714 0.9757 0.9859
MCF 10A Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 962 10359 10507 0.9858 0.9917
MCF 10A Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 962 10117 10315 0.9808 0.9887
MCF 10A Ruxolitinib
0.12
uM
LJP5
 1
O17
 72
hr
 962 10485 10714 0.9786 0.9876
MCF 10A Ruxolitinib
0.12
uM
LJP5
 2
O17
 72
hr
 962 10215 10507 0.9721 0.9837
MCF 10A Ruxolitinib
0.12
uM
LJP5
 3
O17
 72
hr
 962 10198 10315 0.9886 0.9933
MCF 10A Ruxolitinib
0.37
uM
LJP5
 1
O16
 72
hr
 962 10247 10714 0.9564 0.9745
MCF 10A Ruxolitinib
0.37
uM
LJP5
 2
O16
 72
hr
 962 10230 10507 0.9736 0.9845
MCF 10A Ruxolitinib
0.37
uM
LJP5
 3
O16
 72
hr
 962 10026 10315 0.9720 0.9835
MCF 10A Ruxolitinib
1.11
uM
LJP5
 1
O15
 72
hr
 962 9803 10714 0.9150 0.9495
MCF 10A Ruxolitinib
1.11
uM
LJP5
 2
O15
 72
hr
 962 10048 10507 0.9562 0.9742
MCF 10A Ruxolitinib
1.11
uM
LJP5
 3
O15
 72
hr
 962 9810 10315 0.9510 0.9709
MCF 10A Ruxolitinib
3.33
uM
LJP5
 1
O14
 72
hr
 962 9377 10714 0.8752 0.9248
MCF 10A Ruxolitinib
3.33
uM
LJP5
 2
O14
 72
hr
 962 10073 10507 0.9586 0.9756
MCF 10A Ruxolitinib
3.33
uM
LJP5
 3
O14
 72
hr
 962 9571 10315 0.9279 0.9567