LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Ruxolitinib
10
uM
LJP5
 1
O13
 72
hr
 962 7136 10714 0.6660 0.7794
MCF 10A Ruxolitinib
10
uM
LJP5
 2
O13
 72
hr
 962 7703 10507 0.7331 0.8278
MCF 10A Ruxolitinib
10
uM
LJP5
 3
O13
 72
hr
 962 7286 10315 0.7063 0.8068
MCF 10A Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 962 10073 10714 0.9402 0.9648
MCF 10A Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 962 10439 10507 0.9935 0.9962
MCF 10A Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 962 10005 10315 0.9699 0.9822
MCF 10A Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 962 9606 10714 0.8966 0.9382
MCF 10A Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 962 9577 10507 0.9114 0.9469
MCF 10A Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 962 9721 10315 0.9424 0.9656
MCF 10A Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 962 8867 10714 0.8276 0.8941
MCF 10A Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 962 8733 10507 0.8311 0.8955
MCF 10A Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 962 8735 10315 0.8468 0.9052
MCF 10A Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 962 7122 10714 0.6647 0.7784
MCF 10A Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 962 7438 10507 0.7079 0.8094
MCF 10A Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 962 7331 10315 0.7107 0.8101
MCF 10A Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 962 4387 10714 0.4095 0.5471
MCF 10A Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 962 4368 10507 0.4157 0.5506
MCF 10A Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 962 4435 10315 0.4300 0.5628
MCF 10A Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 962 1202 10714 0.1122 0.0661
MCF 10A Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 962 1343 10507 0.1278 0.1015
MCF 10A Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 962 1198 10315 0.1161 0.0662
MCF 10A Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 962 9742 10714 0.9093 0.9460
MCF 10A Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 962 10322 10507 0.9823 0.9897
MCF 10A Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 962 9718 10315 0.9421 0.9655
MCF 10A Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 962 9406 10714 0.8779 0.9265