LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 658 525 3908 0.1343 -0.0842
Hs 578T Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 658 563 3953 0.1424 -0.0586
Hs 578T Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 658 677 3938 0.1719 0.0110
Hs 578T YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 658 3949 3908 1.0104 1.0080
Hs 578T YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 658 4016 3953 1.0158 1.0121
Hs 578T YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 658 3941 3938 1.0007 1.0005
Hs 578T YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 658 3820 3908 0.9774 0.9823
Hs 578T YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 658 3859 3953 0.9760 0.9813
Hs 578T YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 658 3881 3938 0.9854 0.9887
Hs 578T YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 658 3844 3908 0.9835 0.9871
Hs 578T YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 658 3781 3953 0.9563 0.9658
Hs 578T YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 658 3748 3938 0.9517 0.9620
Hs 578T YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 658 3159 3908 0.8082 0.8410
Hs 578T YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 658 3133 3953 0.7924 0.8280
Hs 578T YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 658 3342 3938 0.8486 0.8767
Hs 578T YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 658 2446 3908 0.6258 0.6666
Hs 578T YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 658 2522 3953 0.6379 0.6809
Hs 578T YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 658 2538 3938 0.6444 0.6869
Hs 578T YM 201636
10
uM
LJP5
 1
N07
 72
hr
 658 695 3908 0.1778 0.0214
Hs 578T YM 201636
10
uM
LJP5
 2
N07
 72
hr
 658 881 3953 0.2228 0.1193
Hs 578T YM 201636
10
uM
LJP5
 3
N07
 72
hr
 658 887 3938 0.2252 0.1225
Hs 578T TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 658 4113 3908 1.0523 1.0401
Hs 578T TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 658 4140 3953 1.0471 1.0359
Hs 578T TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 658 3955 3938 1.0042 1.0033
Hs 578T TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 658 3826 3908 0.9789 0.9835