LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Torin1
10
uM
LJP6
 3
O13
 72
hr
 658 484 3769 0.1284 -0.1149
Hs 578T Torin2
0.04
uM
LJP5
 1
I24
 72
hr
 658 945 3908 0.2418 0.1511
Hs 578T Torin2
0.04
uM
LJP5
 2
I24
 72
hr
 658 975 3953 0.2466 0.1641
Hs 578T Torin2
0.04
uM
LJP5
 3
I24
 72
hr
 658 1050 3938 0.2666 0.1984
Hs 578T Torin2
0.12
uM
LJP5
 1
I23
 72
hr
 658 756 3908 0.1934 0.0554
Hs 578T Torin2
0.12
uM
LJP5
 2
I23
 72
hr
 658 777 3953 0.1965 0.0663
Hs 578T Torin2
0.12
uM
LJP5
 3
I23
 72
hr
 658 804 3938 0.2041 0.0806
Hs 578T Torin2
0.37
uM
LJP5
 1
I22
 72
hr
 658 448 3908 0.1146 -0.1390
Hs 578T Torin2
0.37
uM
LJP5
 2
I22
 72
hr
 658 490 3953 0.1239 -0.1078
Hs 578T Torin2
0.37
uM
LJP5
 3
I22
 72
hr
 658 630 3938 0.1600 -0.0168
Hs 578T Torin2
1.11
uM
LJP5
 1
I21
 72
hr
 658 479 3908 0.1226 -0.1163
Hs 578T Torin2
1.11
uM
LJP5
 2
I21
 72
hr
 658 512 3953 0.1295 -0.0925
Hs 578T Torin2
1.11
uM
LJP5
 3
I21
 72
hr
 658 671 3938 0.1704 0.0075
Hs 578T Torin2
3.33
uM
LJP5
 1
I20
 72
hr
 658 525 3908 0.1343 -0.0842
Hs 578T Torin2
3.33
uM
LJP5
 2
I20
 72
hr
 658 506 3953 0.1280 -0.0967
Hs 578T Torin2
3.33
uM
LJP5
 3
I20
 72
hr
 658 568 3938 0.1442 -0.0555
Hs 578T Torin2
10
uM
LJP5
 1
I19
 72
hr
 658 473 3908 0.1210 -0.1206
Hs 578T Torin2
10
uM
LJP5
 2
I19
 72
hr
 658 375 3953 0.0948 -0.1955
Hs 578T Torin2
10
uM
LJP5
 3
I19
 72
hr
 658 495 3938 0.1257 -0.1045
Hs 578T WZ-4-145
0.04
uM
LJP6
 1
J24
 72
hr
 658 2405 3705 0.6490 0.6816
Hs 578T WZ-4-145
0.04
uM
LJP6
 2
J24
 72
hr
 658 2358 3807 0.6193 0.6552
Hs 578T WZ-4-145
0.04
uM
LJP6
 3
J24
 72
hr
 658 2500 3769 0.6632 0.6990
Hs 578T WZ-4-145
0.12
uM
LJP6
 1
J23
 72
hr
 658 2540 3705 0.6854 0.7188
Hs 578T WZ-4-145
0.12
uM
LJP6
 2
J23
 72
hr
 658 2221 3807 0.5833 0.6165
Hs 578T WZ-4-145
0.12
uM
LJP6
 3
J23
 72
hr
 658 2610 3769 0.6924 0.7283