LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 658 501 3807 0.1316 -0.1022
Hs 578T SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 658 564 3769 0.1496 -0.0595
Hs 578T SNS-032
10
uM
LJP6
 1
H13
 72
hr
 658 526 3705 0.1419 -0.0860
Hs 578T SNS-032
10
uM
LJP6
 2
H13
 72
hr
 658 506 3807 0.1329 -0.0986
Hs 578T SNS-032
10
uM
LJP6
 3
H13
 72
hr
 658 526 3769 0.1395 -0.0852
Hs 578T Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 658 3551 3705 0.9582 0.9661
Hs 578T Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 658 3643 3807 0.9568 0.9654
Hs 578T Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 658 3476 3769 0.9221 0.9366
Hs 578T Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 658 3640 3705 0.9822 0.9857
Hs 578T Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 658 3584 3807 0.9413 0.9528
Hs 578T Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 658 3786 3769 1.0043 1.0034
Hs 578T Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 658 3558 3705 0.9601 0.9676
Hs 578T Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 658 3717 3807 0.9762 0.9811
Hs 578T Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 658 3559 3769 0.9441 0.9548
Hs 578T Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 658 3315 3705 0.8945 0.9126
Hs 578T Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 658 3419 3807 0.8980 0.9168
Hs 578T Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 658 3289 3769 0.8725 0.8945
Hs 578T Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 658 3364 3705 0.9078 0.9239
Hs 578T Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 658 3360 3807 0.8825 0.9036
Hs 578T Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 658 3444 3769 0.9136 0.9295
Hs 578T Afatinib
10
uM
LJP6
 1
G19
 72
hr
 658 461 3705 0.1244 -0.1331
Hs 578T Afatinib
10
uM
LJP6
 2
G19
 72
hr
 658 440 3807 0.1156 -0.1470
Hs 578T Afatinib
10
uM
LJP6
 3
G19
 72
hr
 658 470 3769 0.1247 -0.1252
Hs 578T GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 658 3424 3705 0.9239 0.9375
Hs 578T GSK1904529A
0.04
uM
LJP6
 2
H24
 72
hr
 658 3390 3807 0.8903 0.9103