LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 658 1221 3807 0.3207 0.2764
Hs 578T WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 658 1180 3769 0.3130 0.2609
Hs 578T WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 658 1128 3705 0.3044 0.2412
Hs 578T WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 658 1284 3807 0.3372 0.3020
Hs 578T WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 658 1214 3769 0.3220 0.2752
Hs 578T WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 658 1115 3705 0.3009 0.2354
Hs 578T WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 658 1191 3807 0.3128 0.2639
Hs 578T WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 658 1183 3769 0.3138 0.2622
Hs 578T WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 658 1049 3705 0.2831 0.2056
Hs 578T WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 658 1172 3807 0.3078 0.2559
Hs 578T WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 658 1167 3769 0.3096 0.2554
Hs 578T WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 658 1045 3705 0.2820 0.2037
Hs 578T WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 658 1010 3807 0.2653 0.1842
Hs 578T WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 658 988 3769 0.2621 0.1751
Hs 578T Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 658 1279 3908 0.3272 0.2950
Hs 578T Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 658 1243 3953 0.3144 0.2786
Hs 578T Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 658 1257 3938 0.3192 0.2849
Hs 578T Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 658 1268 3908 0.3244 0.2906
Hs 578T Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 658 1207 3953 0.3053 0.2642
Hs 578T Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 658 1166 3938 0.2961 0.2480
Hs 578T Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 658 1087 3908 0.2781 0.2156
Hs 578T Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 658 1249 3953 0.3159 0.2810
Hs 578T Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 658 1150 3938 0.2920 0.2414
Hs 578T Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 658 1264 3908 0.3234 0.2891
Hs 578T Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 658 1159 3953 0.2931 0.2445