LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 658 1229 3938 0.3121 0.2737
Hs 578T Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 658 1156 3908 0.2958 0.2450
Hs 578T Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 658 1175 3953 0.2972 0.2511
Hs 578T Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 658 1134 3938 0.2879 0.2346
Hs 578T Barasertib
10
uM
LJP5
 1
D07
 72
hr
 658 955 3908 0.2443 0.1558
Hs 578T Barasertib
10
uM
LJP5
 2
D07
 72
hr
 658 928 3953 0.2347 0.1420
Hs 578T Barasertib
10
uM
LJP5
 3
D07
 72
hr
 658 932 3938 0.2366 0.1443
Hs 578T Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 658 4107 3908 1.0508 1.0389
Hs 578T Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 658 4001 3953 1.0120 1.0092
Hs 578T Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 658 4133 3938 1.0494 1.0377
Hs 578T Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 658 3954 3908 1.0116 1.0090
Hs 578T Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 658 4016 3953 1.0158 1.0121
Hs 578T Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 658 4124 3938 1.0471 1.0360
Hs 578T Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 658 3786 3908 0.9687 0.9754
Hs 578T Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 658 3848 3953 0.9733 0.9792
Hs 578T Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 658 4043 3938 1.0266 1.0204
Hs 578T Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 658 3703 3908 0.9474 0.9584
Hs 578T Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 658 3644 3953 0.9217 0.9379
Hs 578T Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 658 3779 3938 0.9595 0.9682
Hs 578T Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 658 2949 3908 0.7545 0.7924
Hs 578T Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 658 3138 3953 0.7937 0.8291
Hs 578T Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 658 3034 3938 0.7704 0.8077
Hs 578T Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 658 1963 3908 0.5022 0.5299
Hs 578T Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 658 1962 3953 0.4962 0.5254
Hs 578T Vemurafenib
10
uM
LJP5
 3
C13
 72
hr
 658 1822 3938 0.4626 0.4836