LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T NU7441
10
uM
LJP5
 1
C07
 72
hr
 658 791 3908 0.2024 0.0741
Hs 578T NU7441
10
uM
LJP5
 2
C07
 72
hr
 658 787 3953 0.1991 0.0715
Hs 578T NU7441
10
uM
LJP5
 3
C07
 72
hr
 658 664 3938 0.1686 0.0034
Hs 578T OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 658 3728 3705 1.0060 1.0048
Hs 578T OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 658 3584 3807 0.9413 0.9528
Hs 578T OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 658 3785 3769 1.0041 1.0032
Hs 578T OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 658 3101 3705 0.8368 0.8621
Hs 578T OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 658 3337 3807 0.8764 0.8985
Hs 578T OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 658 3217 3769 0.8534 0.8779
Hs 578T OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 658 2753 3705 0.7429 0.7752
Hs 578T OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 658 2672 3807 0.7018 0.7390
Hs 578T OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 658 2779 3769 0.7372 0.7719
Hs 578T OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 658 1979 3705 0.5340 0.5551
Hs 578T OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 658 2016 3807 0.5295 0.5559
Hs 578T OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 658 1802 3769 0.4780 0.4918
Hs 578T OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 658 1529 3705 0.4126 0.4022
Hs 578T OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 658 1761 3807 0.4625 0.4750
Hs 578T OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 658 1624 3769 0.4308 0.4315
Hs 578T OSI-027
10
uM
LJP6
 1
E07
 72
hr
 658 1218 3705 0.3287 0.2800
Hs 578T OSI-027
10
uM
LJP6
 2
E07
 72
hr
 658 1179 3807 0.3097 0.2589
Hs 578T OSI-027
10
uM
LJP6
 3
E07
 72
hr
 658 1134 3769 0.3008 0.2412
Hs 578T WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 658 1332 3705 0.3594 0.3268
Hs 578T WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 658 1480 3807 0.3887 0.3771
Hs 578T WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 658 1372 3769 0.3640 0.3387
Hs 578T WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 658 1193 3705 0.3219 0.2694