LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Imatinib
10
uM
LJP6
 1
N13
 72
hr
 658 3259 3705 0.8794 0.8995
Hs 578T Imatinib
10
uM
LJP6
 2
N13
 72
hr
 658 3667 3807 0.9631 0.9705
Hs 578T Imatinib
10
uM
LJP6
 3
N13
 72
hr
 658 3415 3769 0.9059 0.9230
Hs 578T NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 658 2963 3705 0.7996 0.8284
Hs 578T NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 658 3148 3807 0.8268 0.8553
Hs 578T NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 658 3129 3769 0.8300 0.8574
Hs 578T NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 658 2494 3705 0.6730 0.7063
Hs 578T NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 658 2630 3807 0.6907 0.7281
Hs 578T NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 658 2625 3769 0.6963 0.7322
Hs 578T NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 658 1830 3705 0.4938 0.5070
Hs 578T NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 658 1999 3807 0.5250 0.5507
Hs 578T NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 658 1910 3769 0.5067 0.5267
Hs 578T NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 658 1342 3705 0.3621 0.3308
Hs 578T NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 658 1166 3807 0.3062 0.2534
Hs 578T NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 658 859 3769 0.2279 0.1116
Hs 578T NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 658 819 3705 0.2210 0.0916
Hs 578T NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 658 815 3807 0.2141 0.0881
Hs 578T NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 658 863 3769 0.2289 0.1136
Hs 578T NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 658 221 3705 0.0596 -0.3545
Hs 578T NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 658 186 3807 0.0489 -0.3929
Hs 578T NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 658 225 3769 0.0597 -0.3471
Hs 578T CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 658 506 3705 0.1365 -0.1001
Hs 578T CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 658 536 3807 0.1408 -0.0779
Hs 578T CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 658 532 3769 0.1411 -0.0811
Hs 578T CGP60474
0.04
uM
LJP5
 1
F06
 72
hr
 658 2753 3908 0.7044 0.7451