LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Tozasertib
0.37
uM
LJP5
3
B16
72
hr
658 757 3938 0.1922 0.0557
Hs 578T Tozasertib
1.11
uM
LJP5
1
B15
72
hr
658 673 3908 0.1722 0.0087
Hs 578T Tozasertib
1.11
uM
LJP5
2
B15
72
hr
658 695 3953 0.1758 0.0213
Hs 578T Tozasertib
1.11
uM
LJP5
3
B15
72
hr
658 780 3938 0.1981 0.0680
Hs 578T Tozasertib
3.33
uM
LJP5
1
B14
72
hr
658 737 3908 0.1886 0.0450
Hs 578T Tozasertib
3.33
uM
LJP5
2
B14
72
hr
658 773 3953 0.1955 0.0641
Hs 578T Tozasertib
3.33
uM
LJP5
3
B14
72
hr
658 864 3938 0.2194 0.1112
Hs 578T Tozasertib
10
uM
LJP5
1
B13
72
hr
658 765 3908 0.1957 0.0603
Hs 578T Tozasertib
10
uM
LJP5
2
B13
72
hr
658 795 3953 0.2011 0.0757
Hs 578T Tozasertib
10
uM
LJP5
3
B13
72
hr
658 798 3938 0.2026 0.0775
Hs 578T Imatinib
0.04
uM
LJP6
1
N18
72
hr
658 3833 3705 1.0343 1.0272
Hs 578T Imatinib
0.04
uM
LJP6
2
N18
72
hr
658 3923 3807 1.0303 1.0237
Hs 578T Imatinib
0.04
uM
LJP6
3
N18
72
hr
658 3670 3769 0.9736 0.9788
Hs 578T Imatinib
0.12
uM
LJP6
1
N17
72
hr
658 3681 3705 0.9933 0.9946
Hs 578T Imatinib
0.12
uM
LJP6
2
N17
72
hr
658 3750 3807 0.9849 0.9880
Hs 578T Imatinib
0.12
uM
LJP6
3
N17
72
hr
658 3699 3769 0.9812 0.9850
Hs 578T Imatinib
0.37
uM
LJP6
1
N16
72
hr
658 3600 3705 0.9714 0.9769
Hs 578T Imatinib
0.37
uM
LJP6
2
N16
72
hr
658 3555 3807 0.9337 0.9465
Hs 578T Imatinib
0.37
uM
LJP6
3
N16
72
hr
658 3748 3769 0.9942 0.9954
Hs 578T Imatinib
1.11
uM
LJP6
1
N15
72
hr
658 3638 3705 0.9817 0.9852
Hs 578T Imatinib
1.11
uM
LJP6
2
N15
72
hr
658 3681 3807 0.9668 0.9735
Hs 578T Imatinib
1.11
uM
LJP6
3
N15
72
hr
658 3697 3769 0.9807 0.9846
Hs 578T Imatinib
3.33
uM
LJP6
1
N14
72
hr
658 3571 3705 0.9636 0.9705
Hs 578T Imatinib
3.33
uM
LJP6
2
N14
72
hr
658 3803 3807 0.9988 0.9991
Hs 578T Imatinib
3.33
uM
LJP6
3
N14
72
hr
658 3815 3769 1.0120 1.0095