LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Barasertib | 10 | uM | LJP5 | 1 | D07 | 72 | hr | 1209 | 1537 | 3980 | 0.3862 | 0.1496 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 2 | D07 | 72 | hr | 1209 | 1425 | 4252 | 0.3351 | 0.0946 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 3 | D07 | 72 | hr | 1209 | 1444 | 4376 | 0.3300 | 0.1002 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 1209 | 3743 | 3980 | 0.9404 | 0.9298 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 2 | C18 | 72 | hr | 1209 | 3810 | 4252 | 0.8959 | 0.8824 |
| MCF7 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 1209 | 4644 | 4376 | 1.0612 | 1.0651 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 1 | C17 | 72 | hr | 1209 | 4188 | 3980 | 1.0522 | 1.0602 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 2 | C17 | 72 | hr | 1209 | 3818 | 4252 | 0.8978 | 0.8846 |
| MCF7 | Vemurafenib | 0.12 | uM | LJP5 | 3 | C17 | 72 | hr | 1209 | 4637 | 4376 | 1.0596 | 1.0634 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 1209 | 4302 | 3980 | 1.0809 | 1.0926 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 2 | C16 | 72 | hr | 1209 | 4461 | 4252 | 1.0490 | 1.0534 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 1209 | 4280 | 4376 | 0.9780 | 0.9762 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 1 | C15 | 72 | hr | 1209 | 4011 | 3980 | 1.0078 | 1.0090 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 2 | C15 | 72 | hr | 1209 | 4129 | 4252 | 0.9709 | 0.9677 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 3 | C15 | 72 | hr | 1209 | 4473 | 4376 | 1.0221 | 1.0237 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 1 | C14 | 72 | hr | 1209 | 4262 | 3980 | 1.0708 | 1.0813 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 2 | C14 | 72 | hr | 1209 | 4098 | 4252 | 0.9636 | 0.9595 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 3 | C14 | 72 | hr | 1209 | 4418 | 4376 | 1.0096 | 1.0103 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 1 | C13 | 72 | hr | 1209 | 3342 | 3980 | 0.8397 | 0.8066 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 2 | C13 | 72 | hr | 1209 | 3749 | 4252 | 0.8815 | 0.8657 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 1209 | 3699 | 4376 | 0.8453 | 0.8267 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 1209 | 3879 | 3980 | 0.9746 | 0.9703 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 2 | D18 | 72 | hr | 1209 | 3887 | 4252 | 0.9140 | 0.9033 |
| MCF7 | Enzastaurin | 0.04 | uM | LJP5 | 3 | D18 | 72 | hr | 1209 | 4368 | 4376 | 0.9981 | 0.9980 |
| MCF7 | Enzastaurin | 0.12 | uM | LJP5 | 1 | D17 | 72 | hr | 1209 | 4096 | 3980 | 1.0291 | 1.0337 |