LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1209 1332 4121 0.3232 0.0560
MCF7 WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 1209 1222 3823 0.3196 0.0062
MCF7 WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 1209 1328 4093 0.3244 0.0545
MCF7 WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 1209 1328 4121 0.3222 0.0542
MCF7 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1209 1219 3823 0.3189 0.0047
MCF7 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1209 1127 4093 0.2753 -0.0394
MCF7 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1209 1164 4121 0.2824 -0.0215
MCF7 WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 1209 843 3823 0.2205 -0.1955
MCF7 WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 1209 894 4093 0.2184 -0.1579
MCF7 WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 1209 901 4121 0.2186 -0.1534
MCF7 Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 1209 1521 3980 0.3822 0.1426
MCF7 Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 1209 1396 4252 0.3283 0.0822
MCF7 Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 1209 1590 4376 0.3633 0.1588
MCF7 Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 1209 1473 3980 0.3701 0.1215
MCF7 Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 1209 1461 4252 0.3435 0.1097
MCF7 Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 1209 1441 4376 0.3293 0.0990
MCF7 Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 1209 1450 3980 0.3643 0.1113
MCF7 Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 1209 1398 4252 0.3287 0.0831
MCF7 Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 1209 1514 4376 0.3460 0.1286
MCF7 Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 1209 1462 3980 0.3673 0.1166
MCF7 Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 1209 1373 4252 0.3229 0.0724
MCF7 Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 1209 1416 4376 0.3236 0.0887
MCF7 Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 1209 1451 3980 0.3646 0.1117
MCF7 Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 1209 1423 4252 0.3346 0.0937
MCF7 Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 1209 1349 4376 0.3083 0.0606