LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 SB590885
10
uM
LJP5
 3
L13
 72
hr
 1209 409 4376 0.0935 -0.4426
MCF7 Pictilisib
0.04
uM
LJP6
 1
D24
 72
hr
 1209 2112 3823 0.5525 0.3990
MCF7 Pictilisib
0.04
uM
LJP6
 2
D24
 72
hr
 1209 2181 4093 0.5328 0.3982
MCF7 Pictilisib
0.04
uM
LJP6
 3
D24
 72
hr
 1209 2114 4121 0.5130 0.3712
MCF7 Pictilisib
0.12
uM
LJP6
 1
D23
 72
hr
 1209 1484 3823 0.3882 0.1311
MCF7 Pictilisib
0.12
uM
LJP6
 2
D23
 72
hr
 1209 1579 4093 0.3857 0.1636
MCF7 Pictilisib
0.12
uM
LJP6
 3
D23
 72
hr
 1209 1749 4121 0.4244 0.2319
MCF7 Pictilisib
0.37
uM
LJP6
 1
D22
 72
hr
 1209 1215 3823 0.3178 0.0027
MCF7 Pictilisib
0.37
uM
LJP6
 2
D22
 72
hr
 1209 1189 4093 0.2904 -0.0097
MCF7 Pictilisib
0.37
uM
LJP6
 3
D22
 72
hr
 1209 1234 4121 0.2994 0.0114
MCF7 Pictilisib
1.11
uM
LJP6
 1
D21
 72
hr
 1209 1224 3823 0.3202 0.0072
MCF7 Pictilisib
1.11
uM
LJP6
 2
D21
 72
hr
 1209 1164 4093 0.2843 -0.0216
MCF7 Pictilisib
1.11
uM
LJP6
 3
D21
 72
hr
 1209 1260 4121 0.3057 0.0234
MCF7 Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 1209 1211 3823 0.3168 0.0007
MCF7 Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 1209 1072 4093 0.2619 -0.0663
MCF7 Pictilisib
3.33
uM
LJP6
 3
D20
 72
hr
 1209 1053 4121 0.2555 -0.0754
MCF7 Pictilisib
10
uM
LJP6
 1
D19
 72
hr
 1209 912 3823 0.2386 -0.1564
MCF7 Pictilisib
10
uM
LJP6
 2
D19
 72
hr
 1209 821 4093 0.2005 -0.1977
MCF7 Pictilisib
10
uM
LJP6
 3
D19
 72
hr
 1209 978 4121 0.2373 -0.1132
MCF7 PD184352
0.04
uM
LJP5
 1
L12
 72
hr
 1209 3349 3980 0.8414 0.8088
MCF7 PD184352
0.04
uM
LJP5
 2
L12
 72
hr
 1209 3075 4252 0.7231 0.6726
MCF7 PD184352
0.04
uM
LJP5
 3
L12
 72
hr
 1209 3394 4376 0.7756 0.7439
MCF7 PD184352
0.12
uM
LJP5
 1
L11
 72
hr
 1209 2680 3980 0.6734 0.5888
MCF7 PD184352
0.12
uM
LJP5
 2
L11
 72
hr
 1209 3156 4252 0.7421 0.6968
MCF7 PD184352
0.12
uM
LJP5
 3
L11
 72
hr
 1209 3192 4376 0.7294 0.6872