LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 2 | H10 | 72 | hr | 1401 | 1664 | 4213 | 0.3949 | 0.1142 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 3 | H10 | 72 | hr | 1401 | 1983 | 4545 | 0.4362 | 0.2268 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 1 | H09 | 72 | hr | 1401 | 1461 | 3978 | 0.3672 | 0.0280 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 2 | H09 | 72 | hr | 1401 | 1368 | 4213 | 0.3247 | -0.0151 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 3 | H09 | 72 | hr | 1401 | 1515 | 4545 | 0.3333 | 0.0469 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 1 | H08 | 72 | hr | 1401 | 1461 | 3978 | 0.3672 | 0.0280 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 2 | H08 | 72 | hr | 1401 | 1372 | 4213 | 0.3256 | -0.0133 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 3 | H08 | 72 | hr | 1401 | 1624 | 4545 | 0.3572 | 0.0907 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 1 | H07 | 72 | hr | 1401 | 1406 | 3978 | 0.3534 | 0.0021 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 2 | H07 | 72 | hr | 1401 | 1264 | 4213 | 0.3000 | -0.0630 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 3 | H07 | 72 | hr | 1401 | 1386 | 4545 | 0.3049 | -0.0065 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 1 | J06 | 72 | hr | 1401 | 3794 | 4139 | 0.9167 | 0.8916 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 2 | J06 | 72 | hr | 1401 | 3486 | 4095 | 0.8512 | 0.8022 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 3 | J06 | 72 | hr | 1401 | 3923 | 4272 | 0.9182 | 0.8967 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 1 | J05 | 72 | hr | 1401 | 3187 | 4139 | 0.7700 | 0.6919 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 2 | J05 | 72 | hr | 1401 | 2834 | 4095 | 0.6920 | 0.5764 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 3 | J05 | 72 | hr | 1401 | 3029 | 4272 | 0.7090 | 0.6149 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 1 | J04 | 72 | hr | 1401 | 2275 | 4139 | 0.5497 | 0.3635 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 2 | J04 | 72 | hr | 1401 | 2261 | 4095 | 0.5521 | 0.3623 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 3 | J04 | 72 | hr | 1401 | 2529 | 4272 | 0.5919 | 0.4435 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 1 | J03 | 72 | hr | 1401 | 1206 | 4139 | 0.2914 | -0.0917 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 2 | J03 | 72 | hr | 1401 | 1123 | 4095 | 0.2742 | -0.1334 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 3 | J03 | 72 | hr | 1401 | 1297 | 4272 | 0.3036 | -0.0471 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 1 | J02 | 72 | hr | 1401 | 1141 | 4139 | 0.2757 | -0.1233 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 2 | J02 | 72 | hr | 1401 | 973 | 4095 | 0.2376 | -0.2101 |