LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 3 | J02 | 72 | hr | 1401 | 1024 | 4272 | 0.2397 | -0.1773 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 1401 | 827 | 4139 | 0.1998 | -0.2866 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 2 | J01 | 72 | hr | 1401 | 752 | 4095 | 0.1836 | -0.3313 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 3 | J01 | 72 | hr | 1401 | 800 | 4272 | 0.1873 | -0.2944 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 1 | I18 | 72 | hr | 1401 | 2084 | 3978 | 0.5238 | 0.3016 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 2 | I18 | 72 | hr | 1401 | 2536 | 4213 | 0.6019 | 0.4527 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 3 | I18 | 72 | hr | 1401 | 2419 | 4545 | 0.5321 | 0.3792 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 1 | I17 | 72 | hr | 1401 | 1538 | 3978 | 0.3866 | 0.0637 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 2 | I17 | 72 | hr | 1401 | 1704 | 4213 | 0.4044 | 0.1310 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 3 | I17 | 72 | hr | 1401 | 1772 | 4545 | 0.3898 | 0.1482 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 1 | I16 | 72 | hr | 1401 | 1310 | 3978 | 0.3293 | -0.0439 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 2 | I16 | 72 | hr | 1401 | 1652 | 4213 | 0.3921 | 0.1091 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 3 | I16 | 72 | hr | 1401 | 1403 | 4545 | 0.3086 | 0.0006 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 1 | I15 | 72 | hr | 1401 | 1418 | 3978 | 0.3564 | 0.0078 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 2 | I15 | 72 | hr | 1401 | 1407 | 4213 | 0.3339 | 0.0025 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 3 | I15 | 72 | hr | 1401 | 1344 | 4545 | 0.2957 | -0.0244 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 1 | I14 | 72 | hr | 1401 | 1626 | 3978 | 0.4087 | 0.1037 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 2 | I14 | 72 | hr | 1401 | 1153 | 4213 | 0.2737 | -0.1157 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 3 | I14 | 72 | hr | 1401 | 1417 | 4545 | 0.3117 | 0.0065 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 1 | I13 | 72 | hr | 1401 | 1265 | 3978 | 0.3180 | -0.0658 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 2 | I13 | 72 | hr | 1401 | 974 | 4213 | 0.2312 | -0.2048 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 3 | I13 | 72 | hr | 1401 | 1024 | 4545 | 0.2253 | -0.1688 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 1 | H18 | 72 | hr | 1401 | 1433 | 3978 | 0.3602 | 0.0149 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 2 | H18 | 72 | hr | 1401 | 1750 | 4213 | 0.4154 | 0.1501 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 3 | H18 | 72 | hr | 1401 | 1749 | 4545 | 0.3847 | 0.1394 |