LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 3 | K23 | 72 | hr | 1401 | 1584 | 4545 | 0.3484 | 0.0748 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 1 | K22 | 72 | hr | 1401 | 1261 | 3978 | 0.3170 | -0.0678 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 2 | K22 | 72 | hr | 1401 | 1342 | 4213 | 0.3185 | -0.0270 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 3 | K22 | 72 | hr | 1401 | 1626 | 4545 | 0.3577 | 0.0915 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 1 | K21 | 72 | hr | 1401 | 1362 | 3978 | 0.3423 | -0.0188 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 2 | K21 | 72 | hr | 1401 | 1399 | 4213 | 0.3320 | -0.0011 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 3 | K21 | 72 | hr | 1401 | 1448 | 4545 | 0.3185 | 0.0194 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 1 | K20 | 72 | hr | 1401 | 1287 | 3978 | 0.3235 | -0.0551 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 2 | K20 | 72 | hr | 1401 | 1428 | 4213 | 0.3389 | 0.0119 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 3 | K20 | 72 | hr | 1401 | 1543 | 4545 | 0.3394 | 0.0583 |
| SK-BR-3 | GDC-0980 | 10 | uM | LJP5 | 1 | K19 | 72 | hr | 1401 | 1281 | 3978 | 0.3220 | -0.0580 |
| SK-BR-3 | GDC-0980 | 10 | uM | LJP5 | 2 | K19 | 72 | hr | 1401 | 1284 | 4213 | 0.3048 | -0.0537 |
| SK-BR-3 | GDC-0980 | 10 | uM | LJP5 | 3 | K19 | 72 | hr | 1401 | 1252 | 4545 | 0.2754 | -0.0643 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP6 | 1 | C24 | 72 | hr | 1401 | 1616 | 4139 | 0.3904 | 0.0954 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP6 | 2 | C24 | 72 | hr | 1401 | 1560 | 4095 | 0.3809 | 0.0717 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP6 | 3 | C24 | 72 | hr | 1401 | 1579 | 4272 | 0.3696 | 0.0770 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP5 | 1 | C24 | 72 | hr | 1401 | 1483 | 3978 | 0.3728 | 0.0383 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP5 | 2 | C24 | 72 | hr | 1401 | 1515 | 4213 | 0.3596 | 0.0503 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP5 | 3 | C24 | 72 | hr | 1401 | 1789 | 4545 | 0.3935 | 0.1546 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 1 | C23 | 72 | hr | 1401 | 1510 | 4139 | 0.3648 | 0.0489 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 2 | C23 | 72 | hr | 1401 | 1439 | 4095 | 0.3514 | 0.0172 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 3 | C23 | 72 | hr | 1401 | 1355 | 4272 | 0.3172 | -0.0208 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 1 | C23 | 72 | hr | 1401 | 1582 | 3978 | 0.3976 | 0.0838 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 2 | C23 | 72 | hr | 1401 | 1558 | 4213 | 0.3698 | 0.0689 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1401 | 1404 | 4545 | 0.3089 | 0.0010 |