LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1401 | 94 | 4095 | 0.0230 | -0.8256 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1401 | 94 | 4139 | 0.0227 | -0.8226 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1235 | 96 | 4474 | 0.0215 | -0.7476 |
| MDA-MB-231 | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1235 | 98 | 4277 | 0.0229 | -0.7571 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1209 | 101 | 4376 | 0.0231 | -0.7377 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1235 | 102 | 4355 | 0.0234 | -0.7466 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1235 | 104 | 4583 | 0.0227 | -0.7299 |
| BT-20 | AZD8055 | 10 | uM | LJP6 | 2 | A07 | 72 | hr | 1097 | 105 | 3713 | 0.0283 | -0.7366 |
| Hs 578T | AZD8055 | 10 | uM | LJP6 | 2 | A07 | 72 | hr | 658 | 109 | 3807 | 0.0286 | -0.5084 |
| Hs 578T | SB590885 | 10 | uM | LJP5 | 2 | L13 | 72 | hr | 658 | 118 | 3953 | 0.0298 | -0.4855 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 120 | 4277 | 0.0281 | -0.7280 |
| MDA-MB-231 | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 1235 | 122 | 4277 | 0.0285 | -0.7255 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1401 | 122 | 4213 | 0.0290 | -0.7851 |
| Hs 578T | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 658 | 122 | 3705 | 0.0329 | -0.4914 |
| BT-20 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1097 | 124 | 3877 | 0.0320 | -0.6979 |
| Hs 578T | SB590885 | 10 | uM | LJP5 | 1 | L13 | 72 | hr | 658 | 124 | 3908 | 0.0317 | -0.4777 |
| BT-20 | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 1097 | 125 | 3610 | 0.0346 | -0.7175 |
| BT-20 | AZD8055 | 10 | uM | LJP6 | 3 | A07 | 72 | hr | 1097 | 129 | 3696 | 0.0349 | -0.7053 |
| MDA-MB-231 | PHA-665752 | 10 | uM | LJP5 | 2 | F13 | 72 | hr | 1235 | 130 | 4578 | 0.0284 | -0.6964 |
| MDA-MB-231 | PHA-665752 | 10 | uM | LJP5 | 3 | F13 | 72 | hr | 1235 | 131 | 4929 | 0.0266 | -0.6752 |
| MDA-MB-231 | PHA-665752 | 10 | uM | LJP5 | 1 | F13 | 72 | hr | 1235 | 133 | 4474 | 0.0297 | -0.6991 |
| MCF 10A | WZ3105 | 10 | uM | LJP5 | 3 | D19 | 72 | hr | 962 | 134 | 10315 | 0.0130 | -0.4379 |
| Hs 578T | SB590885 | 10 | uM | LJP5 | 3 | L13 | 72 | hr | 658 | 135 | 3938 | 0.0343 | -0.4587 |
| MDA-MB-231 | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 1235 | 136 | 4277 | 0.0318 | -0.7083 |
| BT-20 | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1097 | 136 | 3735 | 0.0364 | -0.6932 |