LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | WZ3105 | 3.33 | uM | LJP5 | 1 | D20 | 72 | hr | 962 | 180 | 10714 | 0.0168 | -0.3825 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 962 | 181 | 10641 | 0.0170 | -0.3824 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 962 | 178 | 10315 | 0.0173 | -0.3892 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1209 | 73 | 4121 | 0.0177 | -0.7956 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 962 | 189 | 10641 | 0.0178 | -0.3746 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 88 | 4929 | 0.0179 | -0.7339 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 962 | 193 | 10740 | 0.0180 | -0.3697 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 962 | 193 | 10693 | 0.0180 | -0.3702 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1209 | 69 | 3823 | 0.0180 | -0.8218 |
| MCF 10A | Torin2 | 0.04 | uM | LJP5 | 2 | I24 | 72 | hr | 962 | 189 | 10507 | 0.0180 | -0.3762 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 962 | 195 | 10740 | 0.0182 | -0.3678 |
| MCF 10A | SNS-032 | 3.33 | uM | LJP6 | 1 | H14 | 72 | hr | 962 | 196 | 10693 | 0.0183 | -0.3674 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1209 | 78 | 4252 | 0.0183 | -0.7794 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 2 | A16 | 72 | hr | 962 | 197 | 10740 | 0.0183 | -0.3660 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 962 | 198 | 10693 | 0.0185 | -0.3656 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 3 | A15 | 72 | hr | 962 | 197 | 10641 | 0.0185 | -0.3671 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 962 | 204 | 10693 | 0.0191 | -0.3601 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 962 | 206 | 10693 | 0.0193 | -0.3583 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 962 | 212 | 10693 | 0.0198 | -0.3530 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 962 | 212 | 10693 | 0.0198 | -0.3530 |
| MCF 10A | A443654 | 10 | uM | LJP6 | 2 | I19 | 72 | hr | 962 | 216 | 10740 | 0.0201 | -0.3490 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 962 | 215 | 10693 | 0.0201 | -0.3504 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1401 | 80 | 3978 | 0.0201 | -0.8508 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 2 | G02 | 72 | hr | 962 | 217 | 10740 | 0.0202 | -0.3481 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 962 | 218 | 10740 | 0.0203 | -0.3472 |