LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 1 | D14 | 72 | hr | 962 | 11827 | 10714 | 1.1039 | 1.0577 |
| MCF 10A | CHIR-99021 | 0.37 | uM | LJP6 | 3 | P16 | 72 | hr | 962 | 11725 | 10641 | 1.1018 | 1.0567 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 1 | D15 | 72 | hr | 962 | 11719 | 10714 | 1.0938 | 1.0522 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 3 | P18 | 72 | hr | 962 | 11618 | 10641 | 1.0917 | 1.0513 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 962 | 11598 | 10641 | 1.0899 | 1.0503 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 1 | D13 | 72 | hr | 962 | 11595 | 10714 | 1.0822 | 1.0460 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 3 | J12 | 72 | hr | 962 | 11577 | 10641 | 1.0879 | 1.0492 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 2 | J10 | 72 | hr | 962 | 11555 | 10740 | 1.0758 | 1.0424 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 2 | D14 | 72 | hr | 962 | 11536 | 10507 | 1.0978 | 1.0549 |
| MCF 10A | CHIR-99021 | 0.37 | uM | LJP6 | 2 | P16 | 72 | hr | 962 | 11516 | 10740 | 1.0722 | 1.0404 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 3 | J09 | 72 | hr | 962 | 11496 | 10641 | 1.0803 | 1.0450 |
| MCF 10A | uM | LJP5 | 1 | F12 | 72 | hr | 962 | 11469 | 10714 | 1.0705 | 1.0396 | ||
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 2 | J09 | 72 | hr | 962 | 11431 | 10740 | 1.0643 | 1.0361 |
| MCF 10A | CHIR-99021 | 0.12 | uM | LJP6 | 3 | P17 | 72 | hr | 962 | 11427 | 10641 | 1.0738 | 1.0415 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 1 | J10 | 72 | hr | 962 | 11406 | 10693 | 1.0666 | 1.0375 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 2 | J08 | 72 | hr | 962 | 11395 | 10740 | 1.0609 | 1.0343 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 962 | 11392 | 10740 | 1.0606 | 1.0341 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 962 | 11391 | 10693 | 1.0652 | 1.0367 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 2 | P18 | 72 | hr | 962 | 11373 | 10740 | 1.0589 | 1.0331 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 1 | P18 | 72 | hr | 962 | 11363 | 10693 | 1.0626 | 1.0353 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 962 | 11353 | 10315 | 1.1006 | 1.0568 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 3 | P15 | 72 | hr | 962 | 11330 | 10641 | 1.0647 | 1.0365 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 1 | J09 | 72 | hr | 962 | 11323 | 10693 | 1.0589 | 1.0332 |
| MCF 10A | XMD11-85h | 0.04 | uM | LJP6 | 3 | P24 | 72 | hr | 962 | 11312 | 10641 | 1.0630 | 1.0355 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 3 | J11 | 72 | hr | 962 | 11307 | 10641 | 1.0625 | 1.0353 |