LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Seliciclib
3.33
uM
LJP5
 3
J02
 72
hr
 658 3425 3938 0.8696 0.8946
Hs 578T AT-7519
0.12
uM
LJP6
 2
K05
 72
hr
 658 852 3807 0.2238 0.1073
Hs 578T Seliciclib
0.37
uM
LJP5
 1
J04
 72
hr
 658 3806 3908 0.9738 0.9794
Hs 578T Seliciclib
3.33
uM
LJP5
 2
J02
 72
hr
 658 3354 3953 0.8483 0.8768
Hs 578T AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 658 2657 3705 0.7170 0.7502
Hs 578T AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 658 889 3705 0.2399 0.1281
Hs 578T Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 658 3911 3938 0.9930 0.9946
Hs 578T Seliciclib
0.12
uM
LJP5
 3
J05
 72
hr
 658 3781 3938 0.9600 0.9686
Hs 578T Seliciclib
1.11
uM
LJP5
 1
J03
 72
hr
 658 3583 3908 0.9167 0.9335
Hs 578T Seliciclib
3.33
uM
LJP5
 1
J02
 72
hr
 658 3387 3908 0.8666 0.8916
Hs 578T Seliciclib
10
uM
LJP5
 2
J01
 72
hr
 658 2275 3953 0.5754 0.6152
Hs 578T Seliciclib
10
uM
LJP5
 3
J01
 72
hr
 658 2201 3938 0.5589 0.5963
Hs 578T AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 658 2964 3807 0.7785 0.8117
Hs 578T AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 658 2872 3769 0.7619 0.7952
Hs 578T Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 658 3921 3908 1.0032 1.0025
Hs 578T Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 658 4172 3953 1.0552 1.0420
Hs 578T Seliciclib
0.12
uM
LJP5
 1
J05
 72
hr
 658 3915 3908 1.0017 1.0013
Hs 578T Seliciclib
0.12
uM
LJP5
 2
J05
 72
hr
 658 4005 3953 1.0130 1.0100
Hs 578T Seliciclib
0.37
uM
LJP5
 2
J04
 72
hr
 658 3867 3953 0.9781 0.9829
Hs 578T Seliciclib
0.37
uM
LJP5
 3
J04
 72
hr
 658 3697 3938 0.9387 0.9516
Hs 578T Seliciclib
1.11
uM
LJP5
 2
J03
 72
hr
 658 3466 3953 0.8766 0.9008
Hs 578T Seliciclib
1.11
uM
LJP5
 3
J03
 72
hr
 658 3526 3938 0.8953 0.9161
Hs 578T Seliciclib
10
uM
LJP5
 1
J01
 72
hr
 658 2420 3908 0.6192 0.6597
Hs 578T AT-7519
0.37
uM
LJP6
 1
K04
 72
hr
 658 460 3705 0.1241 -0.1339
Hs 578T AT-7519
0.12
uM
LJP6
 3
K05
 72
hr
 658 952 3769 0.2525 0.1579
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