LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 1209 3814 3980 0.9583 0.9510
MCF7 Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 1209 3754 4252 0.8827 0.8671
MCF7 Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 1209 4088 4376 0.9342 0.9279
MCF7 Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1209 2669 3980 0.6706 0.5850
MCF7 Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1209 2379 4252 0.5594 0.4520
MCF7 Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1209 3074 4376 0.7025 0.6533
MCF7 Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 1209 1858 3980 0.4668 0.2838
MCF7 Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 1209 2099 4252 0.4936 0.3551
MCF7 Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 1209 2246 4376 0.5132 0.3960
MCF7 Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 1209 1570 3980 0.3945 0.1639
MCF7 Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 1209 1775 4252 0.4174 0.2355
MCF7 Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 1209 1726 4376 0.3944 0.2113
MCF7 Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 1209 1613 3980 0.4053 0.1824
MCF7 Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 1209 1580 4252 0.3715 0.1587
MCF7 Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 1209 1769 4376 0.4042 0.2274
MCF7 GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 1209 2634 3980 0.6618 0.5729
MCF7 GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 1209 2775 4252 0.6525 0.5806
MCF7 GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 1209 2975 4376 0.6798 0.6244
MCF7 GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 1209 2308 3980 0.5799 0.4565
MCF7 GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 1209 2214 4252 0.5206 0.3955
MCF7 GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 1209 2337 4376 0.5340 0.4262
MCF7 GSK 690693
0.37
uM
LJP5
 1
F22
 72
hr
 1209 1936 3980 0.4864 0.3149
MCF7 GSK 690693
0.37
uM
LJP5
 2
F22
 72
hr
 1209 1827 4252 0.4296 0.2553
MCF7 GSK 690693
0.37
uM
LJP5
 3
F22
 72
hr
 1209 2266 4376 0.5178 0.4027
MCF7 GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 1209 1890 3980 0.4749 0.2966