LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 PD0325901
1.11
uM
LJP5
 3
C03
 72
hr
 1209 2162 4376 0.4940 0.3676
MCF7 PD0325901
3.33
uM
LJP6
 1
E02
 72
hr
 1209 1660 3823 0.4342 0.2101
MCF7 PD0325901
3.33
uM
LJP6
 2
E02
 72
hr
 1209 1872 4093 0.4573 0.2818
MCF7 PD0325901
3.33
uM
LJP6
 3
E02
 72
hr
 1209 2095 4121 0.5084 0.3642
MCF7 PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 1209 1759 3980 0.4420 0.2435
MCF7 PD0325901
3.33
uM
LJP5
 2
C02
 72
hr
 1209 1894 4252 0.4454 0.2805
MCF7 PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 1209 2182 4376 0.4986 0.3744
MCF7 PD0325901
10
uM
LJP6
 1
E01
 72
hr
 1209 1146 3823 0.2998 -0.0320
MCF7 PD0325901
10
uM
LJP6
 2
E01
 72
hr
 1209 1534 4093 0.3747 0.1446
MCF7 PD0325901
10
uM
LJP6
 3
E01
 72
hr
 1209 1733 4121 0.4205 0.2255
MCF7 PD0325901
10
uM
LJP5
 1
C01
 72
hr
 1209 1420 3980 0.3568 0.0978
MCF7 PD0325901
10
uM
LJP5
 2
C01
 72
hr
 1209 1657 4252 0.3896 0.1895
MCF7 PD0325901
10
uM
LJP5
 3
C01
 72
hr
 1209 1799 4376 0.4111 0.2386
MCF7 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 1209 2196 3823 0.5744 0.4322
MCF7 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 1209 2276 4093 0.5560 0.4325
MCF7 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 1209 2254 4121 0.5469 0.4218
MCF7 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 1209 2213 3980 0.5560 0.4213
MCF7 Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 1209 2597 4252 0.6107 0.5239
MCF7 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 1209 2794 4376 0.6385 0.5703
MCF7 Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 1209 1316 3823 0.3442 0.0521
MCF7 Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 1209 1377 4093 0.3364 0.0765
MCF7 Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 1209 1522 4121 0.3693 0.1387
MCF7 Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 1209 1250 3980 0.3141 0.0193
MCF7 Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 1209 1447 4252 0.3403 0.1039
MCF7 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 1209 1834 4376 0.4191 0.2515