LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 1097 2877 3877 0.7419 0.6977
BT-20 Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 1097 2622 3925 0.6680 0.6059
BT-20 Trametinib
10
uM
LJP5
 1
P19
 72
hr
 1097 2722 3735 0.7287 0.6721
BT-20 Trametinib
10
uM
LJP5
 2
P19
 72
hr
 1097 3100 3877 0.7994 0.7687
BT-20 Trametinib
10
uM
LJP5
 3
P19
 72
hr
 1097 2926 3925 0.7454 0.7047
BT-20 Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 1097 740 3610 0.2050 -0.2049
BT-20 Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 1097 818 3713 0.2203 -0.1538
BT-20 Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 1097 776 3696 0.2099 -0.1794
BT-20 Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 1097 765 3610 0.2119 -0.1893
BT-20 Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 1097 694 3713 0.1869 -0.2293
BT-20 Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 1097 728 3696 0.1970 -0.2088
BT-20 Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 1097 647 3610 0.1792 -0.2647
BT-20 Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 1097 590 3713 0.1589 -0.2972
BT-20 Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 1097 589 3696 0.1593 -0.2989
BT-20 Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 1097 475 3610 0.1316 -0.3857
BT-20 Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 1097 499 3713 0.1344 -0.3611
BT-20 Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 1097 564 3696 0.1526 -0.3160
BT-20 Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 1097 483 3610 0.1338 -0.3797
BT-20 Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 1097 499 3713 0.1344 -0.3611
BT-20 Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 1097 493 3696 0.1334 -0.3666
BT-20 Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 1097 378 3610 0.1047 -0.4622
BT-20 Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 1097 466 3713 0.1255 -0.3855
BT-20 Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 1097 440 3696 0.1190 -0.4064
BT-20 Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 1097 3693 3735 0.9887 0.9872
BT-20 Buparlisib
0.04
uM
LJP5
 2
H06
 72
hr
 1097 4034 3877 1.0403 1.0438