LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 SU11274
10
uM
LJP5
 1
J07
 72
hr
 1097 1329 3735 0.3558 0.1145
BT-20 SU11274
10
uM
LJP5
 2
J07
 72
hr
 1097 1206 3877 0.3110 0.0533
BT-20 SU11274
10
uM
LJP5
 3
J07
 72
hr
 1097 1218 3925 0.3103 0.0584
BT-20 Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 1097 3415 3610 0.9458 0.9362
BT-20 Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 1097 3676 3713 0.9898 0.9884
BT-20 Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 1097 3390 3696 0.9171 0.9036
BT-20 Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 1097 3265 3610 0.9043 0.8863
BT-20 Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 1097 3343 3713 0.9002 0.8839
BT-20 Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 1097 3213 3696 0.8692 0.8463
BT-20 Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 1097 3102 3610 0.8591 0.8309
BT-20 Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 1097 3152 3713 0.8488 0.8220
BT-20 Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 1097 3046 3696 0.8240 0.7909
BT-20 Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 1097 2879 3610 0.7974 0.7531
BT-20 Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 1097 2862 3713 0.7707 0.7247
BT-20 Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 1097 3119 3696 0.8438 0.8152
BT-20 Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 1097 2677 3610 0.7414 0.6804
BT-20 Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 1097 2772 3713 0.7464 0.6936
BT-20 Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 1097 2566 3696 0.6942 0.6239
BT-20 Canertinib
10
uM
LJP6
 1
H07
 72
hr
 1097 723 3610 0.2003 -0.2156
BT-20 Canertinib
10
uM
LJP6
 2
H07
 72
hr
 1097 830 3713 0.2235 -0.1467
BT-20 Canertinib
10
uM
LJP6
 3
H07
 72
hr
 1097 728 3696 0.1970 -0.2088
BT-20 NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 1097 3818 3735 1.0222 1.0250
BT-20 NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 1097 3548 3877 0.9150 0.9047
BT-20 NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 1097 4136 3925 1.0536 1.0576
BT-20 NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 1097 3823 3735 1.0235 1.0265