LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 1097 3574 3735 0.9568 0.9507
BT-20 Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 1097 3642 3877 0.9392 0.9323
BT-20 Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 1097 3401 3925 0.8664 0.8500
BT-20 Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 1097 3101 3735 0.8302 0.8001
BT-20 Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 1097 3239 3877 0.8353 0.8118
BT-20 Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 1097 3098 3925 0.7892 0.7584
BT-20 Fedratinib
3.33
uM
LJP5
 1
L02
 72
hr
 1097 2573 3735 0.6889 0.6197
BT-20 Fedratinib
3.33
uM
LJP5
 2
L02
 72
hr
 1097 2662 3877 0.6865 0.6268
BT-20 Fedratinib
3.33
uM
LJP5
 3
L02
 72
hr
 1097 2558 3925 0.6517 0.5845
BT-20 Fedratinib
10
uM
LJP5
 1
L01
 72
hr
 1097 752 3735 0.2013 -0.1925
BT-20 Fedratinib
10
uM
LJP5
 2
L01
 72
hr
 1097 815 3877 0.2102 -0.1506
BT-20 Fedratinib
10
uM
LJP5
 3
L01
 72
hr
 1097 702 3925 0.1788 -0.2156
BT-20 Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1097 2687 3735 0.7194 0.6599
BT-20 Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 1097 3198 3877 0.8247 0.7992
BT-20 Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1097 3250 3925 0.8279 0.8048
BT-20 Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 1097 2963 3735 0.7933 0.7544
BT-20 Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 1097 2973 3877 0.7667 0.7285
BT-20 Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 1097 3187 3925 0.8119 0.7857
BT-20 Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 1097 2913 3735 0.7799 0.7375
BT-20 Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 1097 2936 3877 0.7571 0.7167
BT-20 Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 1097 2735 3925 0.6967 0.6432
BT-20 Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 1097 2510 3735 0.6720 0.5971
BT-20 Trametinib
1.11
uM
LJP5
 2
P21
 72
hr
 1097 2936 3877 0.7571 0.7167
BT-20 Trametinib
1.11
uM
LJP5
 3
P21
 72
hr
 1097 2833 3925 0.7217 0.6750
BT-20 Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 1097 2750 3735 0.7362 0.6818