LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Ruxolitinib
10
uM
LJP5
 3
O13
 72
hr
 1097 3195 3925 0.8139 0.7882
BT-20 Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 1097 3291 3735 0.8811 0.8617
BT-20 Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 1097 3966 3877 1.0227 1.0249
BT-20 Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 1097 3721 3925 0.9479 0.9427
BT-20 Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 1097 3229 3735 0.8645 0.8418
BT-20 Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 1097 3888 3877 1.0026 1.0029
BT-20 Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 1097 3313 3925 0.8440 0.8238
BT-20 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 1097 3181 3735 0.8516 0.8263
BT-20 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 1097 3730 3877 0.9619 0.9578
BT-20 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 1097 3511 3925 0.8944 0.8823
BT-20 Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 1097 2864 3735 0.7668 0.7209
BT-20 Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 1097 3138 3877 0.8092 0.7806
BT-20 Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 1097 3139 3925 0.7997 0.7711
BT-20 Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 1097 2087 3735 0.5587 0.4388
BT-20 Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 1097 2655 3877 0.6847 0.6244
BT-20 Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 1097 2249 3925 0.5729 0.4774
BT-20 Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 1097 994 3735 0.2661 -0.0544
BT-20 Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 1097 1055 3877 0.2721 -0.0213
BT-20 Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 1097 1138 3925 0.2899 0.0200
BT-20 Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 1097 4162 3735 1.1143 1.1263
BT-20 Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 1097 4023 3877 1.0374 1.0408
BT-20 Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 1097 4135 3925 1.0534 1.0574
BT-20 Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 1097 3931 3735 1.0524 1.0587
BT-20 Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 1097 3806 3877 0.9815 0.9796
BT-20 Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 1097 3574 3925 0.9105 0.9006