LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Linsitinib
1.11
uM
LJP5
 2
O21
 72
hr
 1097 3772 3877 0.9727 0.9699
BT-20 Linsitinib
1.11
uM
LJP5
 3
O21
 72
hr
 1097 3355 3925 0.8547 0.8363
BT-20 Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 1097 3694 3735 0.9890 0.9875
BT-20 Linsitinib
3.33
uM
LJP5
 2
O20
 72
hr
 1097 3643 3877 0.9395 0.9326
BT-20 Linsitinib
3.33
uM
LJP5
 3
O20
 72
hr
 1097 3228 3925 0.8223 0.7982
BT-20 Linsitinib
10
uM
LJP5
 1
O19
 72
hr
 1097 3160 3735 0.8460 0.8194
BT-20 Linsitinib
10
uM
LJP5
 2
O19
 72
hr
 1097 3158 3877 0.8144 0.7868
BT-20 Linsitinib
10
uM
LJP5
 3
O19
 72
hr
 1097 3270 3925 0.8330 0.8109
BT-20 Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 1097 3651 3735 0.9775 0.9744
BT-20 Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 1097 3436 3877 0.8861 0.8715
BT-20 Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 1097 3975 3925 1.0126 1.0137
BT-20 Ruxolitinib
0.12
uM
LJP5
 1
O17
 72
hr
 1097 3699 3735 0.9903 0.9890
BT-20 Ruxolitinib
0.12
uM
LJP5
 2
O17
 72
hr
 1097 3609 3877 0.9307 0.9227
BT-20 Ruxolitinib
0.12
uM
LJP5
 3
O17
 72
hr
 1097 3580 3925 0.9120 0.9023
BT-20 Ruxolitinib
0.37
uM
LJP5
 1
O16
 72
hr
 1097 3740 3735 1.0013 1.0014
BT-20 Ruxolitinib
0.37
uM
LJP5
 2
O16
 72
hr
 1097 3670 3877 0.9464 0.9404
BT-20 Ruxolitinib
0.37
uM
LJP5
 3
O16
 72
hr
 1097 3557 3925 0.9061 0.8956
BT-20 Ruxolitinib
1.11
uM
LJP5
 1
O15
 72
hr
 1097 4065 3735 1.0883 1.0981
BT-20 Ruxolitinib
1.11
uM
LJP5
 2
O15
 72
hr
 1097 3995 3877 1.0302 1.0330
BT-20 Ruxolitinib
1.11
uM
LJP5
 3
O15
 72
hr
 1097 3943 3925 1.0045 1.0049
BT-20 Ruxolitinib
3.33
uM
LJP5
 1
O14
 72
hr
 1097 3916 3735 1.0484 1.0542
BT-20 Ruxolitinib
3.33
uM
LJP5
 2
O14
 72
hr
 1097 3908 3877 1.0078 1.0085
BT-20 Ruxolitinib
3.33
uM
LJP5
 3
O14
 72
hr
 1097 3747 3925 0.9546 0.9500
BT-20 Ruxolitinib
10
uM
LJP5
 1
O13
 72
hr
 1097 3124 3735 0.8364 0.8077
BT-20 Ruxolitinib
10
uM
LJP5
 2
O13
 72
hr
 1097 3125 3877 0.8059 0.7765