LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD8330
1.11
uM
LJP5
 1
G21
 72
hr
 1235 1325 4474 0.2961 0.0382
MDA-MB-231 AZD8330
1.11
uM
LJP5
 2
G21
 72
hr
 1235 1399 4578 0.3056 0.0678
MDA-MB-231 AZD8330
1.11
uM
LJP5
 3
G21
 72
hr
 1235 1382 4929 0.2804 0.0576
MDA-MB-231 AZD8330
3.33
uM
LJP5
 1
G20
 72
hr
 1235 1110 4474 0.2481 -0.0563
MDA-MB-231 AZD8330
3.33
uM
LJP5
 2
G20
 72
hr
 1235 1358 4578 0.2966 0.0511
MDA-MB-231 AZD8330
3.33
uM
LJP5
 3
G20
 72
hr
 1235 1609 4929 0.3264 0.1413
MDA-MB-231 AZD8330
10
uM
LJP5
 1
G19
 72
hr
 1235 1370 4474 0.3062 0.0570
MDA-MB-231 AZD8330
10
uM
LJP5
 2
G19
 72
hr
 1235 1496 4578 0.3267 0.1064
MDA-MB-231 AZD8330
10
uM
LJP5
 3
G19
 72
hr
 1235 1478 4929 0.2998 0.0938
MDA-MB-231 TGX221
0.04
uM
LJP5
 1
H24
 72
hr
 1235 3753 4474 0.8387 0.8192
MDA-MB-231 TGX221
0.04
uM
LJP5
 2
H24
 72
hr
 1235 3755 4578 0.8201 0.8007
MDA-MB-231 TGX221
0.04
uM
LJP5
 3
H24
 72
hr
 1235 4370 4929 0.8865 0.8829
MDA-MB-231 TGX221
0.12
uM
LJP5
 1
H23
 72
hr
 1235 3905 4474 0.8727 0.8585
MDA-MB-231 TGX221
0.12
uM
LJP5
 2
H23
 72
hr
 1235 3925 4578 0.8573 0.8434
MDA-MB-231 TGX221
0.12
uM
LJP5
 3
H23
 72
hr
 1235 4523 4929 0.9176 0.9156
MDA-MB-231 TGX221
0.37
uM
LJP5
 1
H22
 72
hr
 1235 3811 4474 0.8517 0.8343
MDA-MB-231 TGX221
0.37
uM
LJP5
 2
H22
 72
hr
 1235 3990 4578 0.8715 0.8595
MDA-MB-231 TGX221
0.37
uM
LJP5
 3
H22
 72
hr
 1235 4497 4929 0.9123 0.9101
MDA-MB-231 TGX221
1.11
uM
LJP5
 1
H21
 72
hr
 1235 3891 4474 0.8696 0.8549
MDA-MB-231 TGX221
1.11
uM
LJP5
 2
H21
 72
hr
 1235 4157 4578 0.9079 0.9003
MDA-MB-231 TGX221
1.11
uM
LJP5
 3
H21
 72
hr
 1235 4885 4929 0.9910 0.9910
MDA-MB-231 TGX221
3.33
uM
LJP5
 1
H20
 72
hr
 1235 3806 4474 0.8506 0.8330
MDA-MB-231 TGX221
3.33
uM
LJP5
 2
H20
 72
hr
 1235 4226 4578 0.9230 0.9170
MDA-MB-231 TGX221
3.33
uM
LJP5
 3
H20
 72
hr
 1235 4723 4929 0.9582 0.9576
MDA-MB-231 TGX221
10
uM
LJP5
 1
H19
 72
hr
 1235 3855 4474 0.8615 0.8457