LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 1235 585 4929 0.1187 -0.3126
MDA-MB-231 YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 1235 4321 4474 0.9657 0.9627
MDA-MB-231 YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 1235 4657 4578 1.0171 1.0181
MDA-MB-231 YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 1235 5043 4929 1.0231 1.0230
MDA-MB-231 YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 1235 3773 4474 0.8432 0.8244
MDA-MB-231 YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 1235 4057 4578 0.8861 0.8760
MDA-MB-231 YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 1235 4784 4929 0.9705 0.9702
MDA-MB-231 YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 1235 3295 4474 0.7364 0.6960
MDA-MB-231 YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 1235 3538 4578 0.7727 0.7449
MDA-MB-231 YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 1235 4370 4929 0.8865 0.8829
MDA-MB-231 YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 1235 2870 4474 0.6414 0.5744
MDA-MB-231 YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 1235 2928 4578 0.6395 0.5786
MDA-MB-231 YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 1235 3872 4929 0.7855 0.7721
MDA-MB-231 YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 1235 2380 4474 0.5319 0.4234
MDA-MB-231 YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 1235 2653 4578 0.5794 0.4983
MDA-MB-231 YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 1235 3063 4929 0.6214 0.5758
MDA-MB-231 YM 201636
10
uM
LJP5
 1
N07
 72
hr
 1235 866 4474 0.1935 -0.1744
MDA-MB-231 YM 201636
10
uM
LJP5
 2
N07
 72
hr
 1235 1001 4578 0.2186 -0.1056
MDA-MB-231 YM 201636
10
uM
LJP5
 3
N07
 72
hr
 1235 1093 4929 0.2217 -0.0597
MDA-MB-231 TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 1235 3803 4474 0.8499 0.8322
MDA-MB-231 TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 1235 4022 4578 0.8784 0.8674
MDA-MB-231 TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 1235 5137 4929 1.0421 1.0418
MDA-MB-231 TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 1235 3810 4474 0.8515 0.8340
MDA-MB-231 TWS119
0.12
uM
LJP5
 2
M05
 72
hr
 1235 3992 4578 0.8719 0.8600
MDA-MB-231 TWS119
0.12
uM
LJP5
 3
M05
 72
hr
 1235 4832 4929 0.9803 0.9801