LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 1235 1144 4578 0.2499 -0.0401
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 1235 1441 4929 0.2923 0.0799
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 1235 790 4355 0.1814 -0.2183
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 1235 840 4277 0.1964 -0.1940
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 1235 1000 4583 0.2182 -0.1060
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 1235 968 4474 0.2163 -0.1234
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 2
O04
 72
hr
 1235 877 4578 0.1915 -0.1661
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 1235 988 4929 0.2004 -0.1061
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 1235 679 4355 0.1559 -0.2808
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 1235 468 4277 0.1094 -0.4185
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 1235 876 4583 0.1911 -0.1665
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 1
O03
 72
hr
 1235 839 4474 0.1875 -0.1884
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 2
O03
 72
hr
 1235 855 4578 0.1867 -0.1772
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 3
O03
 72
hr
 1235 834 4929 0.1692 -0.1789
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 1235 702 4355 0.1612 -0.2675
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 1235 293 4277 0.0685 -0.5523
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 1235 794 4583 0.1732 -0.2087
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 1235 733 4474 0.1638 -0.2453
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 1235 715 4578 0.1562 -0.2515
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 1235 782 4929 0.1586 -0.2050
MDA-MB-231 Geldanamycin
10
uM
LJP6
 1
O01
 72
hr
 1235 347 4355 0.0797 -0.5029
MDA-MB-231 Geldanamycin
10
uM
LJP6
 2
O01
 72
hr
 1235 149 4277 0.0348 -0.6931
MDA-MB-231 Geldanamycin
10
uM
LJP6
 3
O01
 72
hr
 1235 507 4583 0.1106 -0.3758
MDA-MB-231 Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 1235 586 4474 0.1310 -0.3311
MDA-MB-231 Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 1235 454 4578 0.0992 -0.4115