LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 1235 4509 4929 0.9147 0.9127
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 1
B22
 72
hr
 1235 4369 4474 0.9764 0.9744
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 2
B22
 72
hr
 1235 4453 4578 0.9726 0.9708
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 3
B22
 72
hr
 1235 4538 4929 0.9206 0.9188
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 1
B21
 72
hr
 1235 4275 4474 0.9554 0.9514
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 2
B21
 72
hr
 1235 4216 4578 0.9208 0.9145
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 3
B21
 72
hr
 1235 4311 4929 0.8746 0.8701
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 1
B20
 72
hr
 1235 4195 4474 0.9375 0.9316
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 2
B20
 72
hr
 1235 4305 4578 0.9403 0.9358
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 3
B20
 72
hr
 1235 4233 4929 0.8588 0.8531
MDA-MB-231 Sigma A6730
10
uM
LJP5
 1
B19
 72
hr
 1235 2476 4474 0.5533 0.4540
MDA-MB-231 Sigma A6730
10
uM
LJP5
 2
B19
 72
hr
 1235 2992 4578 0.6535 0.5967
MDA-MB-231 Sigma A6730
10
uM
LJP5
 3
B19
 72
hr
 1235 2618 4929 0.5311 0.4566
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 1
O12
 72
hr
 1235 3732 4474 0.8340 0.8137
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 2
O12
 72
hr
 1235 3420 4578 0.7470 0.7138
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 3
O12
 72
hr
 1235 4172 4929 0.8464 0.8396
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 1
O11
 72
hr
 1235 3033 4474 0.6778 0.6220
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 2
O11
 72
hr
 1235 3193 4578 0.6974 0.6526
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 3
O11
 72
hr
 1235 3734 4929 0.7575 0.7402
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 1
O10
 72
hr
 1235 1351 4474 0.3019 0.0491
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 2
O10
 72
hr
 1235 1189 4578 0.2597 -0.0203
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 3
O10
 72
hr
 1235 1348 4929 0.2735 0.0444
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 1
O09
 72
hr
 1235 774 4474 0.1730 -0.2229
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 2
O09
 72
hr
 1235 874 4578 0.1909 -0.1676
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 3
O09
 72
hr
 1235 935 4929 0.1897 -0.1305