LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 KIN001-043
10
uM
LJP6
 2
C07
 72
hr
 1235 884 4277 0.2067 -0.1707
MDA-MB-231 KIN001-043
10
uM
LJP6
 3
C07
 72
hr
 1235 1363 4583 0.2974 0.0531
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 1235 3546 4355 0.8141 0.7860
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 1235 3526 4277 0.8243 0.7955
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 1235 3708 4583 0.8090 0.7879
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 1235 3084 4355 0.7080 0.6539
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 1235 3279 4277 0.7666 0.7242
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 1235 3419 4583 0.7460 0.7128
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 1235 2875 4355 0.6600 0.5913
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 1235 2725 4277 0.6371 0.5549
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 1235 3201 4583 0.6984 0.6542
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 1235 2706 4355 0.6212 0.5391
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 1235 2917 4277 0.6820 0.6152
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 1235 2882 4583 0.6288 0.5648
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 1235 2570 4355 0.5900 0.4960
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 1235 2428 4277 0.5676 0.4579
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 1235 2882 4583 0.6288 0.5648
MDA-MB-231 Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 1235 1927 4355 0.4424 0.2768
MDA-MB-231 Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 1235 1921 4277 0.4491 0.2792
MDA-MB-231 Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 1235 2402 4583 0.5241 0.4211
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1235 4591 4474 1.0260 1.0278
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 1235 4347 4578 0.9494 0.9458
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 1235 4595 4929 0.9322 0.9309
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 1235 4428 4474 0.9896 0.9887
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 2
B23
 72
hr
 1235 4462 4578 0.9745 0.9729