LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 1235 4514 4277 1.0553 1.0610
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 1235 4828 4583 1.0534 1.0558
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 1235 4201 4355 0.9644 0.9605
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 1235 4400 4277 1.0287 1.0318
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 1235 5106 4583 1.1140 1.1175
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 1235 4389 4355 1.0076 1.0083
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 1235 4157 4277 0.9719 0.9684
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 1235 4765 4583 1.0396 1.0415
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 1235 4340 4355 0.9963 0.9960
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 1235 4485 4277 1.0485 1.0536
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 1235 5098 4583 1.1123 1.1158
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 1235 4425 4355 1.0159 1.0174
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 1235 4195 4277 0.9808 0.9784
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 1235 4873 4583 1.0632 1.0659
MDA-MB-231 Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 1235 3699 4355 0.8492 0.8280
MDA-MB-231 Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 1235 3551 4277 0.8302 0.8026
MDA-MB-231 Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 1235 4209 4583 0.9183 0.9119
MDA-MB-231 CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 1235 4427 4474 0.9893 0.9885
MDA-MB-231 CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 1235 4664 4578 1.0187 1.0197
MDA-MB-231 CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 1235 4996 4929 1.0135 1.0135
MDA-MB-231 CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 1235 4023 4474 0.8991 0.8886
MDA-MB-231 CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 1235 4772 4578 1.0422 1.0443
MDA-MB-231 CP466722
0.12
uM
LJP5
 3
I11
 72
hr
 1235 4816 4929 0.9770 0.9768
MDA-MB-231 CP466722
0.37
uM
LJP5
 1
I10
 72
hr
 1235 4364 4474 0.9753 0.9732
MDA-MB-231 CP466722
0.37
uM
LJP5
 2
I10
 72
hr
 1235 1 4578 0.0002 -0.9769