LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD7762
3.33
uM
LJP6
 1
L02
 72
hr
 1235 476 4355 0.1093 -0.4085
MDA-MB-231 AZD7762
3.33
uM
LJP6
 2
L02
 72
hr
 1235 533 4277 0.1246 -0.3747
MDA-MB-231 AZD7762
3.33
uM
LJP6
 3
L02
 72
hr
 1235 483 4583 0.1054 -0.3916
MDA-MB-231 AZD7762
10
uM
LJP6
 1
L01
 72
hr
 1235 419 4355 0.0962 -0.4486
MDA-MB-231 AZD7762
10
uM
LJP6
 2
L01
 72
hr
 1235 336 4277 0.0786 -0.5167
MDA-MB-231 AZD7762
10
uM
LJP6
 3
L01
 72
hr
 1235 473 4583 0.1032 -0.3983
MDA-MB-231 AZD8055
0.04
uM
LJP6
 1
A12
 72
hr
 1235 2287 4355 0.5250 0.4030
MDA-MB-231 AZD8055
0.04
uM
LJP6
 2
A12
 72
hr
 1235 2819 4277 0.6591 0.5846
MDA-MB-231 AZD8055
0.04
uM
LJP6
 3
A12
 72
hr
 1235 2727 4583 0.5950 0.5197
MDA-MB-231 AZD8055
0.12
uM
LJP6
 1
A11
 72
hr
 1235 1867 4355 0.4286 0.2548
MDA-MB-231 AZD8055
0.12
uM
LJP6
 2
A11
 72
hr
 1235 2444 4277 0.5714 0.4633
MDA-MB-231 AZD8055
0.12
uM
LJP6
 3
A11
 72
hr
 1235 2229 4583 0.4863 0.3660
MDA-MB-231 AZD8055
0.37
uM
LJP6
 1
A10
 72
hr
 1235 1669 4355 0.3832 0.1797
MDA-MB-231 AZD8055
0.37
uM
LJP6
 2
A10
 72
hr
 1235 2136 4277 0.4994 0.3572
MDA-MB-231 AZD8055
0.37
uM
LJP6
 3
A10
 72
hr
 1235 1767 4583 0.3855 0.2081
MDA-MB-231 AZD8055
1.11
uM
LJP6
 1
A09
 72
hr
 1235 1570 4355 0.3604 0.1407
MDA-MB-231 AZD8055
1.11
uM
LJP6
 2
A09
 72
hr
 1235 1908 4277 0.4461 0.2743
MDA-MB-231 AZD8055
1.11
uM
LJP6
 3
A09
 72
hr
 1235 1765 4583 0.3851 0.2074
MDA-MB-231 AZD8055
3.33
uM
LJP6
 1
A08
 72
hr
 1235 1262 4355 0.2897 0.0115
MDA-MB-231 AZD8055
3.33
uM
LJP6
 2
A08
 72
hr
 1235 1125 4277 0.2630 -0.0512
MDA-MB-231 AZD8055
3.33
uM
LJP6
 3
A08
 72
hr
 1235 1566 4583 0.3417 0.1334
MDA-MB-231 AZD8055
10
uM
LJP6
 1
A07
 72
hr
 1235 490 4355 0.1125 -0.3990
MDA-MB-231 AZD8055
10
uM
LJP6
 2
A07
 72
hr
 1235 486 4277 0.1136 -0.4062
MDA-MB-231 AZD8055
10
uM
LJP6
 3
A07
 72
hr
 1235 711 4583 0.1551 -0.2536
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 1235 4616 4355 1.0597 1.0648