LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Dactolisib | 0.37 | uM | LJP5 | 1 | M16 | 72 | hr | 1389 | 1732 | 5772 | 0.3000 | 0.1133 |
| MCF7 | Dactolisib | 0.37 | uM | LJP5 | 3 | M16 | 72 | hr | 1389 | 1849 | 6038 | 0.3062 | 0.1444 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 1 | M15 | 72 | hr | 1389 | 1787 | 5772 | 0.3096 | 0.1304 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 3 | M15 | 72 | hr | 1389 | 1781 | 6038 | 0.2949 | 0.1244 |
| MCF7 | Dactolisib | 3.33 | uM | LJP5 | 1 | M14 | 72 | hr | 1389 | 1786 | 5772 | 0.3094 | 0.1301 |
| MCF7 | Dactolisib | 3.33 | uM | LJP5 | 3 | M14 | 72 | hr | 1389 | 1937 | 6038 | 0.3208 | 0.1698 |
| MCF7 | Dactolisib | 10 | uM | LJP5 | 1 | M13 | 72 | hr | 1389 | 1801 | 5772 | 0.3120 | 0.1347 |
| MCF7 | Dactolisib | 10 | uM | LJP5 | 3 | M13 | 72 | hr | 1389 | 1907 | 6038 | 0.3158 | 0.1612 |
| MCF7 | Alpelisib | 0.04 | uM | LJP5 | 1 | N06 | 72 | hr | 1389 | 5630 | 5772 | 0.9753 | 0.9758 |
| MCF7 | Alpelisib | 0.04 | uM | LJP5 | 3 | N06 | 72 | hr | 1389 | 5574 | 6038 | 0.9231 | 0.9259 |
| MCF7 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 1389 | 4316 | 5772 | 0.7477 | 0.7361 |
| MCF7 | Alpelisib | 0.12 | uM | LJP5 | 3 | N05 | 72 | hr | 1389 | 4551 | 6038 | 0.7537 | 0.7502 |
| MCF7 | Alpelisib | 0.37 | uM | LJP5 | 1 | N04 | 72 | hr | 1389 | 3713 | 5772 | 0.6432 | 0.6135 |
| MCF7 | Alpelisib | 0.37 | uM | LJP5 | 3 | N04 | 72 | hr | 1389 | 4022 | 6038 | 0.6661 | 0.6511 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 1389 | 2856 | 5772 | 0.4948 | 0.4201 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1389 | 3241 | 6038 | 0.5367 | 0.4913 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 1389 | 2255 | 5772 | 0.3907 | 0.2659 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 1389 | 2617 | 6038 | 0.4334 | 0.3482 |
| MCF7 | Alpelisib | 10 | uM | LJP5 | 1 | N01 | 72 | hr | 1389 | 1374 | 5772 | 0.2380 | -0.0053 |
| MCF7 | Alpelisib | 10 | uM | LJP5 | 3 | N01 | 72 | hr | 1389 | 1547 | 6038 | 0.2562 | 0.0521 |
| MCF7 | GDC-0980 | 0.04 | uM | LJP5 | 1 | K24 | 72 | hr | 1389 | 2230 | 5772 | 0.3863 | 0.2590 |
| MCF7 | GDC-0980 | 0.04 | uM | LJP5 | 3 | K24 | 72 | hr | 1389 | 2123 | 6038 | 0.3516 | 0.2215 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1389 | 1408 | 5772 | 0.2439 | 0.0066 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 3 | K23 | 72 | hr | 1389 | 1507 | 6038 | 0.2496 | 0.0392 |
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 1 | K22 | 72 | hr | 1389 | 1235 | 5772 | 0.2140 | -0.0556 |