LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 3 | K22 | 72 | hr | 1389 | 1486 | 6038 | 0.2461 | 0.0323 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 1 | K21 | 72 | hr | 1389 | 1221 | 5772 | 0.2115 | -0.0608 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 3 | K21 | 72 | hr | 1389 | 1250 | 6038 | 0.2070 | -0.0485 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 1 | K20 | 72 | hr | 1389 | 1227 | 5772 | 0.2126 | -0.0586 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 3 | K20 | 72 | hr | 1389 | 1552 | 6038 | 0.2570 | 0.0537 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 1 | K19 | 72 | hr | 1389 | 1237 | 5772 | 0.2143 | -0.0549 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 3 | K19 | 72 | hr | 1389 | 1340 | 6038 | 0.2219 | -0.0168 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 1 | C24 | 72 | hr | 1389 | 1469 | 5147 | 0.2854 | 0.0301 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 2 | C24 | 72 | hr | 1389 | 1585 | 5447 | 0.2909 | 0.0692 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 3 | C24 | 72 | hr | 1389 | 1524 | 5740 | 0.2655 | 0.0463 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 1 | C24 | 72 | hr | 1389 | 1571 | 5772 | 0.2722 | 0.0617 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 3 | C24 | 72 | hr | 1389 | 1737 | 6038 | 0.2877 | 0.1112 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 1 | C23 | 72 | hr | 1389 | 1250 | 5147 | 0.2429 | -0.0543 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 2 | C23 | 72 | hr | 1389 | 1379 | 5447 | 0.2531 | -0.0037 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 3 | C23 | 72 | hr | 1389 | 1498 | 5740 | 0.2610 | 0.0376 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 1 | C23 | 72 | hr | 1389 | 1559 | 5772 | 0.2701 | 0.0578 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1389 | 1651 | 6038 | 0.2734 | 0.0849 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 1 | C22 | 72 | hr | 1389 | 1167 | 5147 | 0.2267 | -0.0881 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 2 | C22 | 72 | hr | 1389 | 1308 | 5447 | 0.2401 | -0.0300 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 3 | C22 | 72 | hr | 1389 | 1412 | 5740 | 0.2460 | 0.0080 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 1 | C22 | 72 | hr | 1389 | 1559 | 5772 | 0.2701 | 0.0578 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 3 | C22 | 72 | hr | 1389 | 1732 | 6038 | 0.2868 | 0.1097 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 1 | C21 | 72 | hr | 1389 | 1096 | 5147 | 0.2129 | -0.1179 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 2 | C21 | 72 | hr | 1389 | 1109 | 5447 | 0.2036 | -0.1079 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 3 | C21 | 72 | hr | 1389 | 1243 | 5740 | 0.2165 | -0.0528 |