LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | LJP5 | 3 | N23 | 72 | hr | 1389 | 6003 | 6038 | 0.9941 | 0.9945 | |||
| MCF7 | LJP5 | 3 | N24 | 72 | hr | 1389 | 5146 | 6038 | 0.8522 | 0.8547 | |||
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 2543 | 5790 | 5734 | 1.0097 | 1.0165 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 2 | J06 | 72 | hr | 2543 | 5743 | 5761 | 0.9968 | 0.9946 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 2543 | 5740 | 5760 | 0.9964 | 0.9939 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 1 | J05 | 72 | hr | 2543 | 5897 | 5734 | 1.0283 | 1.0482 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 2 | J05 | 72 | hr | 2543 | 5782 | 5761 | 1.0036 | 1.0061 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 2543 | 5926 | 5760 | 1.0287 | 1.0485 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 1 | J04 | 72 | hr | 2543 | 5709 | 5734 | 0.9956 | 0.9924 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 2 | J04 | 72 | hr | 2543 | 5263 | 5761 | 0.9135 | 0.8523 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 3 | J04 | 72 | hr | 2543 | 5965 | 5760 | 1.0354 | 1.0599 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 2543 | 5369 | 5734 | 0.9363 | 0.8908 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 2 | J03 | 72 | hr | 2543 | 5357 | 5761 | 0.9298 | 0.8803 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 2543 | 5456 | 5760 | 0.9471 | 0.9099 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 1 | J02 | 72 | hr | 2543 | 4785 | 5734 | 0.8344 | 0.7140 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 2 | J02 | 72 | hr | 2543 | 4809 | 5761 | 0.8347 | 0.7160 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 2543 | 4621 | 5760 | 0.8021 | 0.6590 |
| SK-BR-3 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 2543 | 3039 | 5734 | 0.5300 | 0.1639 |
| SK-BR-3 | Seliciclib | 10 | uM | LJP5 | 2 | J01 | 72 | hr | 2543 | 2994 | 5761 | 0.5197 | 0.1483 |
| SK-BR-3 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 2543 | 2963 | 5760 | 0.5143 | 0.1382 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 2543 | 5098 | 5258 | 0.9694 | 0.9416 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 2 | K06 | 72 | hr | 2543 | 5162 | 5438 | 0.9492 | 0.9072 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 3 | K06 | 72 | hr | 2543 | 5161 | 5557 | 0.9287 | 0.8730 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 2543 | 3334 | 5258 | 0.6340 | 0.2947 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 2 | K05 | 72 | hr | 2543 | 3092 | 5438 | 0.5686 | 0.1950 |