LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 1694 11388 11042 1.0313 1.0229
MCF 10A Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 1694 10969 11099 0.9882 0.9913
MCF 10A Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 1694 11420 11168 1.0225 1.0164
MCF 10A Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 1694 11272 11042 1.0208 1.0153
MCF 10A Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 1694 11039 11099 0.9946 0.9960
MCF 10A Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 1694 11162 11168 0.9994 0.9996
MCF 10A Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 1694 11172 11042 1.0117 1.0087
MCF 10A Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 1694 11239 11099 1.0126 1.0092
MCF 10A Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 1694 11463 11168 1.0264 1.0192
MCF 10A Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 1694 11358 11042 1.0286 1.0210
MCF 10A Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 1694 10893 11099 0.9814 0.9862
MCF 10A Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 1694 11123 11168 0.9959 0.9970
MCF 10A Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 1694 6058 11042 0.5486 0.6018
MCF 10A Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 1694 5320 11099 0.4793 0.5249
MCF 10A Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 1694 6578 11168 0.5890 0.6464
MCF 10A JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 1694 11340 11220 1.0106 1.0078
MCF 10A JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 1694 12018 11309 1.0627 1.0449
MCF 10A JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 1694 10992 11121 0.9884 0.9914
MCF 10A JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 1694 10758 11220 0.9587 0.9693
MCF 10A JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 1694 10887 11309 0.9627 0.9724
MCF 10A JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 1694 10527 11121 0.9466 0.9600
MCF 10A JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 1694 9290 11220 0.8279 0.8662
MCF 10A JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 1694 9202 11309 0.8137 0.8550
MCF 10A JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 1694 9127 11121 0.8207 0.8596
MCF 10A JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 1694 2934 11220 0.2615 0.2230