LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 1694 8123 11121 0.7304 0.7814
MCF 10A Palbociclib
0.37
uM
LJP6
 1
E16
 72
hr
 1694 7176 11220 0.6395 0.6977
MCF 10A Palbociclib
0.37
uM
LJP6
 2
E16
 72
hr
 1694 7357 11309 0.6505 0.7094
MCF 10A Palbociclib
0.37
uM
LJP6
 3
E16
 72
hr
 1694 7322 11121 0.6584 0.7146
MCF 10A Palbociclib
1.11
uM
LJP6
 1
E15
 72
hr
 1694 6498 11220 0.5791 0.6370
MCF 10A Palbociclib
1.11
uM
LJP6
 2
E15
 72
hr
 1694 6192 11309 0.5475 0.6051
MCF 10A Palbociclib
1.11
uM
LJP6
 3
E15
 72
hr
 1694 6186 11121 0.5562 0.6114
MCF 10A Palbociclib
3.33
uM
LJP6
 1
E14
 72
hr
 1694 5572 11220 0.4966 0.5473
MCF 10A Palbociclib
3.33
uM
LJP6
 2
E14
 72
hr
 1694 5663 11309 0.5007 0.5536
MCF 10A Palbociclib
3.33
uM
LJP6
 3
E14
 72
hr
 1694 5615 11121 0.5049 0.5549
MCF 10A Palbociclib
10
uM
LJP6
 1
E13
 72
hr
 1694 4793 11220 0.4272 0.4642
MCF 10A Palbociclib
10
uM
LJP6
 2
E13
 72
hr
 1694 4727 11309 0.4180 0.4545
MCF 10A Palbociclib
10
uM
LJP6
 3
E13
 72
hr
 1694 4470 11121 0.4019 0.4296
MCF 10A PF562271
0.04
uM
LJP6
 1
F18
 72
hr
 1694 9434 11220 0.8408 0.8768
MCF 10A PF562271
0.04
uM
LJP6
 2
F18
 72
hr
 1694 9600 11309 0.8489 0.8839
MCF 10A PF562271
0.04
uM
LJP6
 3
F18
 72
hr
 1694 9418 11121 0.8469 0.8812
MCF 10A PF562271
0.12
uM
LJP6
 1
F17
 72
hr
 1694 8547 11220 0.7617 0.8100
MCF 10A PF562271
0.12
uM
LJP6
 2
F17
 72
hr
 1694 8609 11309 0.7612 0.8104
MCF 10A PF562271
0.12
uM
LJP6
 3
F17
 72
hr
 1694 8685 11121 0.7809 0.8259
MCF 10A PF562271
0.37
uM
LJP6
 1
F16
 72
hr
 1694 6837 11220 0.6093 0.6678
MCF 10A PF562271
0.37
uM
LJP6
 2
F16
 72
hr
 1694 6851 11309 0.6058 0.6655
MCF 10A PF562271
0.37
uM
LJP6
 3
F16
 72
hr
 1694 7073 11121 0.6360 0.6929
MCF 10A PF562271
1.11
uM
LJP6
 1
F15
 72
hr
 1694 5160 11220 0.4599 0.5043
MCF 10A PF562271
1.11
uM
LJP6
 2
F15
 72
hr
 1694 5114 11309 0.4522 0.4969
MCF 10A PF562271
1.11
uM
LJP6
 3
F15
 72
hr
 1694 5321 11121 0.4785 0.5244