LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Vemurafenib | 10 | uM | LJP5 | 2 | C13 | 72 | hr | 1694 | 5605 | 11099 | 0.5050 | 0.5546 |
| MCF 10A | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 1694 | 4885 | 11168 | 0.4374 | 0.4758 |
| MCF 10A | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 1694 | 11021 | 11042 | 0.9981 | 0.9986 |
| MCF 10A | Enzastaurin | 0.04 | uM | LJP5 | 2 | D18 | 72 | hr | 1694 | 11539 | 11099 | 1.0396 | 1.0288 |
| MCF 10A | Enzastaurin | 0.04 | uM | LJP5 | 3 | D18 | 72 | hr | 1694 | 11124 | 11168 | 0.9960 | 0.9971 |
| MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 1 | D17 | 72 | hr | 1694 | 10765 | 11042 | 0.9749 | 0.9813 |
| MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 2 | D17 | 72 | hr | 1694 | 11463 | 11099 | 1.0327 | 1.0239 |
| MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 3 | D17 | 72 | hr | 1694 | 11202 | 11168 | 1.0030 | 1.0022 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 1 | D16 | 72 | hr | 1694 | 10946 | 11042 | 0.9913 | 0.9935 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 2 | D16 | 72 | hr | 1694 | 11323 | 11099 | 1.0201 | 1.0148 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 3 | D16 | 72 | hr | 1694 | 11265 | 11168 | 1.0087 | 1.0063 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 1 | D15 | 72 | hr | 1694 | 11207 | 11042 | 1.0149 | 1.0110 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 2 | D15 | 72 | hr | 1694 | 11880 | 11099 | 1.0703 | 1.0508 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 3 | D15 | 72 | hr | 1694 | 11605 | 11168 | 1.0391 | 1.0284 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 1 | D14 | 72 | hr | 1694 | 11317 | 11042 | 1.0249 | 1.0183 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 2 | D14 | 72 | hr | 1694 | 12082 | 11099 | 1.0885 | 1.0635 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1694 | 11592 | 11168 | 1.0379 | 1.0276 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 1 | D13 | 72 | hr | 1694 | 11802 | 11042 | 1.0688 | 1.0498 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 2 | D13 | 72 | hr | 1694 | 12204 | 11099 | 1.0995 | 1.0712 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 3 | D13 | 72 | hr | 1694 | 12078 | 11168 | 1.0814 | 1.0584 |
| MCF 10A | Palbociclib | 0.04 | uM | LJP6 | 1 | E18 | 72 | hr | 1694 | 9141 | 11220 | 0.8146 | 0.8552 |
| MCF 10A | Palbociclib | 0.04 | uM | LJP6 | 2 | E18 | 72 | hr | 1694 | 9134 | 11309 | 0.8077 | 0.8499 |
| MCF 10A | Palbociclib | 0.04 | uM | LJP6 | 3 | E18 | 72 | hr | 1694 | 9073 | 11121 | 0.8158 | 0.8555 |
| MCF 10A | Palbociclib | 0.12 | uM | LJP6 | 1 | E17 | 72 | hr | 1694 | 8136 | 11220 | 0.7251 | 0.7776 |
| MCF 10A | Palbociclib | 0.12 | uM | LJP6 | 2 | E17 | 72 | hr | 1694 | 7856 | 11309 | 0.6947 | 0.7509 |