LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 1694 2511 11168 0.2248 0.1556
MCF 10A Erlotinib
10
uM
LJP5
 1
M19
 72
hr
 1694 2791 11042 0.2528 0.2027
MCF 10A Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 1694 2476 11099 0.2231 0.1502
MCF 10A Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 1694 2542 11168 0.2276 0.1608
MCF 10A Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 1694 10433 11220 0.9298 0.9473
MCF 10A Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 1694 9836 11309 0.8697 0.9006
MCF 10A Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 1694 9748 11121 0.8765 0.9052
MCF 10A Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 1694 6566 11220 0.5852 0.6433
MCF 10A Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 1694 7387 11309 0.6532 0.7120
MCF 10A Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 1694 7018 11121 0.6311 0.6880
MCF 10A Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 1694 3439 11220 0.3065 0.2964
MCF 10A Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 1694 3949 11309 0.3492 0.3620
MCF 10A Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 1694 4015 11121 0.3610 0.3742
MCF 10A Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 1694 2230 11220 0.1987 0.1060
MCF 10A Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 1694 2396 11309 0.2119 0.1349
MCF 10A Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 1694 2154 11121 0.1937 0.0925
MCF 10A Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 1694 2521 11220 0.2247 0.1569
MCF 10A Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 1694 2654 11309 0.2347 0.1781
MCF 10A Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 1694 2251 11121 0.2024 0.1103
MCF 10A Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 1694 2280 11220 0.2032 0.1150
MCF 10A Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 1694 2356 11309 0.2083 0.1279
MCF 10A Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 1694 2293 11121 0.2062 0.1179
MCF 10A Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 1694 11410 11042 1.0333 1.0244
MCF 10A Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 1694 11263 11099 1.0147 1.0108
MCF 10A Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 1694 11425 11168 1.0230 1.0168