LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | HG-5-88-01 | 3.33 | uM | LJP6 | 3 | A20 | 72 | hr | 1694 | 6309 | 11121 | 0.5673 | 0.6231 |
| MCF 10A | HG-5-88-01 | 10 | uM | LJP6 | 1 | A19 | 72 | hr | 1694 | 5557 | 11220 | 0.4952 | 0.5457 |
| MCF 10A | HG-5-88-01 | 10 | uM | LJP6 | 2 | A19 | 72 | hr | 1694 | 5654 | 11309 | 0.4999 | 0.5527 |
| MCF 10A | HG-5-88-01 | 10 | uM | LJP6 | 3 | A19 | 72 | hr | 1694 | 5344 | 11121 | 0.4805 | 0.5268 |
| MCF 10A | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 1694 | 11069 | 11220 | 0.9865 | 0.9900 |
| MCF 10A | HG-6-64-01 | 0.04 | uM | LJP6 | 2 | M06 | 72 | hr | 1694 | 11805 | 11309 | 1.0438 | 1.0316 |
| MCF 10A | HG-6-64-01 | 0.04 | uM | LJP6 | 3 | M06 | 72 | hr | 1694 | 10994 | 11121 | 0.9886 | 0.9916 |
| MCF 10A | HG-6-64-01 | 0.12 | uM | LJP6 | 1 | M05 | 72 | hr | 1694 | 11079 | 11220 | 0.9874 | 0.9907 |
| MCF 10A | HG-6-64-01 | 0.12 | uM | LJP6 | 2 | M05 | 72 | hr | 1694 | 11699 | 11309 | 1.0345 | 1.0249 |
| MCF 10A | HG-6-64-01 | 0.12 | uM | LJP6 | 3 | M05 | 72 | hr | 1694 | 10754 | 11121 | 0.9670 | 0.9754 |
| MCF 10A | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1694 | 11196 | 11220 | 0.9978 | 0.9984 |
| MCF 10A | HG-6-64-01 | 0.37 | uM | LJP6 | 2 | M04 | 72 | hr | 1694 | 11480 | 11309 | 1.0151 | 1.0110 |
| MCF 10A | HG-6-64-01 | 0.37 | uM | LJP6 | 3 | M04 | 72 | hr | 1694 | 11294 | 11121 | 1.0155 | 1.0114 |
| MCF 10A | HG-6-64-01 | 1.11 | uM | LJP6 | 1 | M03 | 72 | hr | 1694 | 10578 | 11220 | 0.9427 | 0.9572 |
| MCF 10A | HG-6-64-01 | 1.11 | uM | LJP6 | 2 | M03 | 72 | hr | 1694 | 10441 | 11309 | 0.9232 | 0.9425 |
| MCF 10A | HG-6-64-01 | 1.11 | uM | LJP6 | 3 | M03 | 72 | hr | 1694 | 10362 | 11121 | 0.9317 | 0.9486 |
| MCF 10A | HG-6-64-01 | 3.33 | uM | LJP6 | 1 | M02 | 72 | hr | 1694 | 7919 | 11220 | 0.7057 | 0.7601 |
| MCF 10A | HG-6-64-01 | 3.33 | uM | LJP6 | 2 | M02 | 72 | hr | 1694 | 7115 | 11309 | 0.6291 | 0.6887 |
| MCF 10A | HG-6-64-01 | 3.33 | uM | LJP6 | 3 | M02 | 72 | hr | 1694 | 6267 | 11121 | 0.5635 | 0.6191 |
| MCF 10A | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 1694 | 2869 | 11220 | 0.2557 | 0.2130 |
| MCF 10A | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1694 | 2237 | 11309 | 0.1978 | 0.1068 |
| MCF 10A | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 1694 | 1051 | 11121 | 0.0945 | -0.1613 |
| MCF 10A | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1694 | 5523 | 11042 | 0.5002 | 0.5480 |
| MCF 10A | Neratinib | 0.04 | uM | LJP5 | 2 | A18 | 72 | hr | 1694 | 6018 | 11099 | 0.5422 | 0.5959 |
| MCF 10A | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1694 | 5379 | 11168 | 0.4816 | 0.5290 |